A decade of microfluidic analysis coupled with electrospray mass spectrometry: An overview

S Koster, E Verpoorte - Lab on a Chip, 2007 - pubs.rsc.org
This review presents a thorough overview covering the period 1997–2006 of microfluidic
chips coupled to mass spectrometry through an electrospray interface. The different types of …

Electrochemistry/mass spectrometry as a tool in metabolism studies—a review

H Faber, M Vogel, U Karst - Analytica Chimica Acta, 2014 - Elsevier
The combination of electrochemistry (EC) and mass spectrometry (MS) has become a more
and more frequently used approach in metabolism studies in the last decade. This review …

Electrochemistry coupled to (liquid chromatography/) mass spectrometry—current state and future perspectives

S Jahn, U Karst - Journal of chromatography A, 2012 - Elsevier
The coupling of electrochemistry (EC) to different mass spectrometric (MS) techniques in off-
line and especially in on-line approaches is a quickly growing research field in analytical …

Mass spectrometric methods for monitoring redox processes in electrochemical cells

H Oberacher, F Pitterl, R Erb… - Mass spectrometry …, 2015 - Wiley Online Library
Electrochemistry (EC) is a mature scientific discipline aimed to study the movement of
electrons in an oxidation–reduction reaction. EC covers techniques that use a measurement …

Online electrochemistry/mass spectrometry in drug metabolism studies: principles and applications

A Baumann, U Karst - Expert opinion on drug metabolism & …, 2010 - Taylor & Francis
Importance of the field: Conventional metabolism studies in early stages of drug
development include in vitro tests, often based on hepatic cells and cell extracts, as well as …

Online coupling of electrochemical reactions with liquid sample desorption electrospray ionization-mass spectrometry

J Li, HD Dewald, H Chen - Analytical chemistry, 2009 - ACS Publications
The combination of electrochemistry (EC) and mass spectrometry (MS) is a powerful
analytical tool to study redox reactions. This work reports the online coupling of a thin-layer …

Cysteine tagging for MS‐based proteomics

P Giron, L Dayon, JC Sanchez - Mass spectrometry reviews, 2011 - Wiley Online Library
Amino acid‐tagging strategies are widespread in proteomics. Because of the central role of
mass spectrometry (MS) as a detection technique in protein sciences, the term “mass …

Mass spectrometric detection of short-lived drug metabolites generated in an electrochemical microfluidic chip

FTG van den Brink, L Büter, M Odijk… - Analytical …, 2015 - ACS Publications
The costs of drug development have been rising exponentially over the last six decades,
making it essential to select drug candidates in the early drug discovery phases before …

Recent advances of electrochemical mass spectrometry

P Liu, M Lu, Q Zheng, Y Zhang, HD Dewald, H Chen - Analyst, 2013 - pubs.rsc.org
Recent advances of electrochemical mass spectrometry - Analyst (RSC Publishing) DOI:10.1039/C3AN00709J
Royal Society of Chemistry View PDF VersionPrevious ArticleNext Article DOI: 10.1039/C3AN00709J …

Site-selective fragmentation of peptides and proteins at quinone-modified cysteine residues investigated by ESI-MS

JK Diedrich, RR Julian - Analytical chemistry, 2010 - ACS Publications
Described herein are several unique analytical applications utilizing mass spectrometry and
the selective modification of the free thiol form of cysteine in both peptides and proteins by …