No evidence for cardiomyocyte number expansion in preadolescent mice
K Alkass, J Panula, M Westman, TD Wu… - Cell, 2015 - cell.com
The magnitude of cardiomyocyte generation in the adult heart has been heavily debated. A
recent report suggests that during mouse preadolescence, cardiomyocyte proliferation leads …
recent report suggests that during mouse preadolescence, cardiomyocyte proliferation leads …
Limited regeneration potential with minimal epicardial progenitor conversions in the neonatal mouse heart after injury
W Cai, J Tan, J Yan, L Zhang, X Cai, H Wang, F Liu… - Cell reports, 2019 - cell.com
The regeneration capacity of neonatal mouse heart is controversial. In addition, whether
epicardial cells provide a progenitor pool for de novo heart regeneration is incompletely …
epicardial cells provide a progenitor pool for de novo heart regeneration is incompletely …
DUSP5 expression in left ventricular cardiomyocytes of young hearts regulates thyroid hormone (T3)-induced proliferative ERK1/2 signaling
N Bogush, L Tan, H Naib, E Faizullabhoy… - Scientific Reports, 2020 - nature.com
Cardiomyocytes of newborn mice proliferate after injury or exposure to growth factors.
However, these responses are diminished after postnatal day-6 (P6), representing a barrier …
However, these responses are diminished after postnatal day-6 (P6), representing a barrier …
Novel large-particle FACS purification of adult ventricular myocytes reveals accumulation of myosin and actin disproportionate to cell size and proteome in normal post …
JE López, J Sharma, J Avila, TS Wood… - Journal of molecular and …, 2017 - Elsevier
Rationale Quantifying cellular proteins in ventricular myocytes (MCs) is challenging due to
tissue heterogeneity and the variety of cell sizes in the heart. In post-weaning cardiac …
tissue heterogeneity and the variety of cell sizes in the heart. In post-weaning cardiac …
[图书][B] Regulation of cardiac form and function: small RNAs and large hearts
WJ Wijnen - 2015 - dare.uva.nl
MicroRNAs (miRNAs) regulate many aspects of cellular function and their deregulation has
been implicated in heart disease. MiRNA-30c is differentially expressed in the heart during …
been implicated in heart disease. MiRNA-30c is differentially expressed in the heart during …