High-density lipoproteins comprise roughly 25–30% of the circulating proteins involved in
the transport of lipids in circulation. These particles differ in size and lipid composition …

In obese individuals, atherogenic dyslipidemia is a very common and important factor in the
increased risk of cardiovascular disease. Adiposity-associated dyslipidemia is characterized …

The initial discovery that ob/ob mice become obese because of a recessive mutation of the
leptin gene has been crucial to discover the melanocortin pathway to control appetite. In the …

Several prospective epidemiological studies have shown that there is a clear inverse
relationship between serum high-density lipoprotein-cholesterol (HDL-C) concentrations …

High Density Lipoprotein (HDL) particles, beyond serving as lipid transporters and playing a
key role in reverse cholesterol transport, carry a highly variable number of proteins, micro …

Obesity is the most common nutritional disorder worldwide and is associated with
dyslipidemia and atherosclerotic cardiovascular disease. The hallmark of dyslipidemia in …

Background: Obesity increases the risk of coronary heart disease, partly due to its strong
association with atherogenic dyslipidemia, characterized by high triglycerides and low high …

The cholesterol concentrations of low-density lipoprotein (LDL) and high-density lipoprotein
(HDL) have traditionally served as risk factors for cardiovascular disease. As such, novel …

Inflammation and oxidative stress are essential components in a myriad of pathogenic
entities that lead to metabolic and chronic diseases. Moreover, inflammation in its different …

Background Smoking is the most preventable cause of most chronic diseases such as
cardiovascular disease (CVD). Dyslipidemia is also an important risk factor for CVD. Yet …