Oxygen therapy can be delivered using low-flow, intermediate-flow (air entrainment mask),
or high-flow devices. Low/intermediate-flow oxygen devices have several drawbacks that …

High flow nasal cannula (HFNC) supportive therapy has emerged as a safe, useful therapy
in patients with respiratory failure, improving oxygenation and comfort. Recently several …

Introduction: Respiratory drug delivery is a surprisingly complex process with a number of
physical and biological challenges. Computational fluid dynamics (CFD) is a scientific …

Ideally, inhaled therapy is driven by the needs of specific disease management. Lung
biology interfaces with inhaler performance to allow optimal delivery of therapeutic agent for …

Delivery of medications to preterm neonates receiving non-invasive ventilation (NIV)
represents one of the most challenging scenarios for aerosol medicine. This challenge is …

The repurposing of drug delivery by the pulmonary route has been applied to treatment and
prophylaxis of an increasingly wide range of respiratory diseases. Repurposing has been …

Nebulizers have a number of advantages for the delivery of inhaled pharmaceutical
aerosols, including the use of aqueous formulations and the ability to deliver process …

Background: High-flow nasal cannula use is developing in ICUs. The aim of this study was
to compare aerosol efficiency by using two nebulizers through a high-flow nasal cannula …

In this Series paper, we review the current evidence for the use of high-flow oxygen therapy,
inhaled gases, and aerosols in the care of critically ill patients. The available evidence …

While dry powder aerosol formulations offer a number of advantages, their use in children is
often limited due to poor lung delivery efficiency and difficulties with consistent dry powder …