Sustainability assessment of mechanochemistry by using the twelve principles of green chemistry

KJ Ardila‐Fierro, JG Hernández - ChemSusChem, 2021 - Wiley Online Library
In recent years, mechanochemistry has been growing into a widely accepted alternative for
chemical synthesis. In addition to their efficiency and practicality, mechanochemical …

Tribochemistry, mechanical alloying, mechanochemistry: what is in a name?

AAL Michalchuk, EV Boldyreva, AM Belenguer… - Frontiers in …, 2021 - frontiersin.org
Over the decades, the application of mechanical force to influence chemical reactions has
been called by various names: mechanochemistry, tribochemistry, mechanical alloying, to …

Mechanochemistry-directed ligand design: Development of a high-performance phosphine ligand for palladium-catalyzed mechanochemical organoboron cross …

T Seo - Palladium-Catalyzed Mechanochemical Cross …, 2024 - Springer
Mechanochemical synthesis with transition-metal catalysts has attracted significant attention
because of its numerous advantages, including reduced solvent waste, shorter reaction …

Multicomponent mechanochemical synthesis

M Leonardi, M Villacampa, JC Menéndez - Chemical Science, 2018 - pubs.rsc.org
Historically, the use of mechanochemical methods in synthesis has been almost negligible,
but their perception by the synthetic community has changed in recent years and they are on …

Towards medicinal mechanochemistry: evolution of milling from pharmaceutical solid form screening to the synthesis of active pharmaceutical ingredients (APIs)

D Tan, L Loots, T Friščić - Chemical Communications, 2016 - pubs.rsc.org
This overview highlights the emergent area of mechanochemical reactions for making active
pharmaceutical ingredients (APIs), and covers the latest advances in the recently …

Mechanochemistry for organic chemists: an update

D Tan, T Friščić - European Journal of Organic Chemistry, 2018 - Wiley Online Library
We provide a brief overview of recent advances in the use of mechanochemical techniques
for the synthesis of organic molecules and materials, highlighting selected examples of …

Recent advances in the synthesis of hydantoins: the state of the art of a valuable scaffold

L Konnert, F Lamaty, J Martinez, E Colacino - Chemical Reviews, 2017 - ACS Publications
The review highlights the hydantoin syntheses presented from the point of view of the
preparation methods. Novel synthetic routes to various hydantoin structures, the advances …

Raman spectroscopy for real-time and in situ monitoring of mechanochemical milling reactions

S Lukin, K Užarević, I Halasz - Nature Protocols, 2021 - nature.com
Solid-state milling has emerged as an alternative, sustainable approach for preparing
virtually all classes of compounds and materials. In situ reaction monitoring is essential to …

Screening for new pharmaceutical solid forms using mechanochemistry: A practical guide

D Hasa, W Jones - Advanced drug delivery reviews, 2017 - Elsevier
Within the pharmaceutical industry, and elsewhere, the screening for new solid forms is a
mandatory exercise for both existing and new chemical entities. This contribution focuses on …

Tinkering with mechanochemical tools for scale up

JF Reynes, V Isoni, F García - … Chemie International Edition, 2023 - Wiley Online Library
Mechanochemistry provides an environmentally benign platform to develop more
sustainable chemical processes by limiting raw materials, energy use, and waste generation …