Recent advances in the design of microfluidic technologies for the manufacture of drug releasing particles

A Forigua, RL Kirsch, SM Willerth, KS Elvira - Journal of Controlled Release, 2021 - Elsevier
Drug releasing particles are valued for their ability to deliver therapeutics to targeted
locations and for their controllable release patterns. The development of microfluidic …

Overview on therapeutic applications of microparticulate drug delivery systems

S Bale, A Khurana, ASS Reddy… - Critical Reviews™ in …, 2016 - dl.begellhouse.com
Research in novel drug delivery systems is being explored competitively in order to attain
maximum therapeutic effect while minimizing the adverse effects. Despite several …

[HTML][HTML] The management of Parkinson's disease: An overview of the current advancements in drug delivery systems

DD Nakmode, CM Day, Y Song, S Garg - Pharmaceutics, 2023 - mdpi.com
Parkinson's disease (PD) has significantly affected a large proportion of the elderly
population worldwide. According to the World Health Organization, approximately 8.5 million …

Role of neurotrophic factors in Parkinson's disease

D Tome, C Pais Fonseca… - Current …, 2017 - ingentaconnect.com
Parkinson's disease is an age-associated progressive neurodegenerative disorder that has
gained crescent social and economic impact due to the aging of the western society. All …

Primary tissue for cellular brain repair in Parkinson's disease: Promise, problems and the potential of biomaterials

N Moriarty, CL Parish, E Dowd - European Journal of …, 2019 - Wiley Online Library
The dopamine precursor, levodopa, remains the “gold standard” treatment for Parkinson's
disease, and, although it provides superlative efficacy in the early stages of the disease, its …

[HTML][HTML] Development of a glial cell-derived neurotrophic factor-releasing artificial dura for neural tissue engineering applications

NK Mohtaram, J Ko, A Agbay, D Rattray… - Journal of Materials …, 2015 - pubs.rsc.org
Encapsulated electrospun nanofibers can serve as an artificial dura mater, the membrane
that surrounds the brain and spinal cord, due to their desirable drug delivery properties …

Prospects for polymer therapeutics in Parkinson's disease and other neurodegenerative disorders

B Newland, H Newland, C Werner, A Rosser… - Progress in Polymer …, 2015 - Elsevier
Parkinson's disease (PD) is characterized by a progressive loss of dopaminergic neurons
and represents a growing health burden to western societies. Like many neurodegenerative …

Guggulsterone-releasing microspheres direct the differentiation of human induced pluripotent stem cells into neural phenotypes

A Agbay, L De La Vega, G Nixon… - Biomedical Materials, 2018 - iopscience.iop.org
Abstract Parkinson's disease (PD), a common neurodegenerative disorder, results from the
loss of motor function when dopaminergic neurons (DNs) in the brain selectively …

An engineered biocompatible drug delivery system enhances nerve regeneration after delayed repair

K Tajdaran, T Gordon, MD Wood… - … Research Part A, 2016 - Wiley Online Library
Localized drug delivery strategies could greatly benefit patients with peripheral nerve injury
and could be easy for surgeons to implement. We developed a local drug delivery system …

Incorporation of retinoic acid releasing microspheres into pluripotent stem cell aggregates for inducing neuronal differentiation

JC Gomez, JM Edgar, AM Agbay, E Bibault… - Cellular and Molecular …, 2015 - Springer
Pluripotent stem cells (PSCs) can form any specialized cell type found in the body making
them an excellent tool for regenerative medicine applications. Directed differentiation of …