The human 25-kDa Lipocalin 2 (LCN2) was first identified and purified as a protein that in
part is associated with gelatinase from neutrophils. This protein shows a high degree of …

Esophageal squamous cell carcinoma (ESCC) is a common malignancy without effective
therapy. The exomes of more than 600 ESCCs have been sequenced in the past 4 years …

The pathogenesis of any given human disease is a complex multifactorial process
characterized by many biologically significant and interdependent alterations. One of these …

Lipocalin 2 (LCN2) is a secreted protein that belongs to the Lipocalins, a group of
transporters of small lipophilic molecules such as steroids, lipopolysaccharides, iron, and …

Epigenetic alterations such as DNA methylation have been implicated in the development
and progression of various cancers. DNA methylation consists of the reversible addition of a …

MicroRNAs (miRNAs) are short noncoding RNAs that play important roles in cellular
processes and disease pathogenesis via the control of specific targeted gene expression …

Several features of cancer cells such as proliferation, invasion, metastatic spreading, and
drug resistance are affected by their interaction with several tumor microenvironment (TME) …

Gastric carcinogenesis is a complex multistep process involving genetic dysregulation of
proto-oncogenes and tumorsuppressor genes, and has recently entered the era of …

Lipocalin 2 is a protein that has garnered a great deal of interest in multidisciplinary fields
over the last two decades since its discovery. However, its exact function in metabolic …

Cancer is a leading cause of mortalities worldwide. Over the past few decades, exploration
of molecular mechanisms behind cancer initiation and progression has been of great …