Rat models of human diseases and related phenotypes: a systematic inventory of the causative genes

C Szpirer - Journal of biomedical science, 2020 - Springer
The laboratory rat has been used for a long time as the model of choice in several
biomedical disciplines. Numerous inbred strains have been isolated, displaying a wide …

Stress in groups: lessons from non-traditional rodent species and housing models

AK Beery, MM Holmes, W Lee, JP Curley - Neuroscience & Biobehavioral …, 2020 - Elsevier
A major feature of life in groups is that individuals experience social stressors of varying
intensity and type. Social stress can have profound effects on health, social behavior, and …

[图书][B] Handbook of laboratory animal science: Animal Models, Volume III

J Hau, SJ Schapiro, GL Van Hoosier Jr - 2004 - taylorfrancis.com
Building upon the success of the Handbook of Laboratory Animal Science and completing
Volumes I and II of the Second Edition, Handbook of Laboratory Animal Science, Second …

Standardization of an ex vivo method for determination of intestinal permeability of drugs using everted rat intestine apparatus

P Dixit, DK Jain, J Dumbwani - Journal of pharmacological and …, 2012 - Elsevier
INTRODUCTION: Everted gut sac of rat intestine is a paradigm widely employed for
determination of absorption kinetics of drugs along with evaluation of effects of absorption …

The evolutionary history of wild and domestic brown rats (Rattus norvegicus)

J Munshi-South, JA Garcia, D Orton, M Phifer-Rixey - Science, 2024 - science.org
The brown rat (Rattus norvegicus) occupies nearly every terrestrial habitat with a human
presence and is one of our most important model organisms. Despite this prevalence, gaps …

relevant conditions and pathology of laboratory mice, rats, gerbils, Guinea pigs, hamsters, naked mole rats, and rabbits

TK Cooper, DK Meyerholz, AP Beck, MA Delaney… - ILAR …, 2021 - academic.oup.com
Animals are valuable resources in biomedical research in investigations of biological
processes, disease pathogenesis, therapeutic interventions, safety, toxicity, and …

Optimized protocols for sperm cryopreservation and in vitro fertilization in the rat

T Takeo, S Nakao, N Mikoda, K Yamaga, R Maeda… - Lab Animal, 2022 - nature.com
Laboratory rats have been used in biomedical research for over 170 years. Recently,
genome editing technology has facilitated the generation of genetically modified rats …

Biological potential of polyphenols in the context of metabolic syndrome: an analysis of studies on animal models

J Niewiadomska, A Gajek-Marecka, J Gajek… - Biology, 2022 - mdpi.com
Simple Summary Polyphenols are a family of widespread organic compounds occurring in
heterogeneous plants. The antioxidative properties of polyphenols are widely known …

Tyramine stimulates glucose uptake in insulin-sensitive tissues in vitro and in vivo via its oxidation by amine oxidases

N Morin, V Visentin, D Calise, L Marti, A Zorzano… - … of Pharmacology and …, 2002 - ASPET
Tyramine and benzylamine have been described as stimulators of glucose transport in
adipocytes. This effect is dependent on amine oxidation by monoamine oxidase (MAO) or …

immunostimulating study of active agent fraction from Sungkai (Peronema canescens Jack.) leaf from SARS-COV-2 virus antigen exposure to NK and CD8+ T cells

D Dillasamola, FS Wahyuni, RS Rita, Y Alen… - Pharmacognosy …, 2022 - phcogj.com
Introduction: Sungkai (Peronema canescens Jack.) plant had been used as an immune
system enhancer. Aim: In this study, the effect of Sungkai leaf extracts from 4 different …