Cannabidiol: pharmacology and therapeutic targets
SC Britch, S Babalonis, SL Walsh - Psychopharmacology, 2021 - Springer
Rationale Cannabidiol (CBD) products lacking regulatory approval are being used to self-
treat a myriad of conditions and for their unsubstantiated health benefits. The scientific …
treat a myriad of conditions and for their unsubstantiated health benefits. The scientific …
[HTML][HTML] The effects of cannabidiol, a non-intoxicating compound of cannabis, on the cardiovascular system in health and disease
A Kicman, M Toczek - International journal of molecular sciences, 2020 - mdpi.com
Cannabidiol (CBD) is a non-intoxicating and generally well-tolerated constituent of cannabis
which exhibits potential beneficial properties in a wide range of diseases, including …
which exhibits potential beneficial properties in a wide range of diseases, including …
[HTML][HTML] The therapeutic potential of purified cannabidiol
SE O'Sullivan, SS Jensen, GN Nikolajsen… - Journal of Cannabis …, 2023 - Springer
The use of cannabidiol (CBD) for therapeutic purposes is receiving considerable attention,
with speculation that CBD can be useful in a wide range of conditions. Only one product, a …
with speculation that CBD can be useful in a wide range of conditions. Only one product, a …
A placebo‐controlled investigation of the analgesic effects, abuse liability, safety and tolerability of a range of oral cannabidiol doses in healthy humans
Aims Preclinical studies demonstrate that cannabidiol (CBD) elicits an antinociceptive
response in animal models of neuropathic pain; in humans, limited data are available to …
response in animal models of neuropathic pain; in humans, limited data are available to …
Serious adverse effects of cannabidiol (CBD): a review of randomized controlled trials
RG Dos Santos, FS Guimarães… - Expert opinion on …, 2020 - Taylor & Francis
Introduction Recent trials using cannabidiol (CBD) have shown that most acute and
prolonged adverse effects of CBD are mild to moderate, with rare serious adverse effects …
prolonged adverse effects of CBD are mild to moderate, with rare serious adverse effects …
[HTML][HTML] Comparison of five oral cannabidiol preparations in adult humans: pharmacokinetics, body composition, and heart rate variability
NNB Williams, TR Ewell, KSS Abbotts, KJ Harms… - Pharmaceuticals, 2021 - mdpi.com
Data supporting the physiological effects of cannabidiol (CBD) ingestion in humans are
conflicting. Differences between CBD preparations and bioavailability may contribute to …
conflicting. Differences between CBD preparations and bioavailability may contribute to …
[HTML][HTML] CBD supplementation reduces arterial blood pressure via modulation of the sympatho-chromaffin system: A substudy from the HYPER-H21-4 trial
M Kumric, G Dujic, J Vrdoljak, K Svagusa… - Biomedicine & …, 2023 - Elsevier
Data concerning the effects of cannabidiol (CBD) on blood pressure (BP) is controversial.
HYPER-H21–4 was a randomized, placebo-controlled, crossover trial which sought to …
HYPER-H21–4 was a randomized, placebo-controlled, crossover trial which sought to …
[HTML][HTML] Cannabidiol ameliorates monocrotaline-induced pulmonary hypertension in rats
O Sadowska, M Baranowska-Kuczko… - International Journal of …, 2020 - mdpi.com
Cannabidiol (CBD) is known for its vasorelaxant (including in the human pulmonary artery),
anti-proliferative and anti-inflammatory properties. The aim of our study was to examine the …
anti-proliferative and anti-inflammatory properties. The aim of our study was to examine the …
Could cannabidiol be a treatment for coronavirus disease-19-related anxiety disorders?
SE O'Sullivan, CW Stevenson… - Cannabis and …, 2021 - liebertpub.com
Coronavirus disease-19 (COVID-19)-related anxiety and post-traumatic stress symptoms
(PTSS) or post-traumatic stress disorder (PTSD) are likely to be a significant long-term issue …
(PTSS) or post-traumatic stress disorder (PTSD) are likely to be a significant long-term issue …
Chronic effects of oral cannabidiol delivery on 24-h ambulatory blood pressure in patients with hypertension (HYPER-H21-4): a randomized, placebo-controlled, and …
Background: Recent data indicate that cannabidiol (CBD), a nonintoxicating constituent of
cannabis, is involved in several aspects of cardiovascular regulation, including blood …
cannabis, is involved in several aspects of cardiovascular regulation, including blood …