With aging, the progressive loss of skeletal muscle will have negative effect on multiple
physiological parameters, such as exercise, respiration, thermoregulation, and metabolic …

The complexity of human DNA has been affected by aerobic metabolism, including
endurance exercise and oxygen toxicity. Aerobic endurance exercise could play an …

Some of the most serious consequences of ageing are its effects on skeletal muscle. The
term 'sarcopenia'describes the slow but progressive loss of muscle mass with advancing …

Skeletal muscle is the most abundant tissue in the human body, and the maintenance of its
mass is essential to ensure basic function as locomotion, strength and respiration. The …

Aging is characterized by a progressive decline of physiological integrity leading to the loss
of tissue function and vulnerability to disease, but its causes remain poorly understood …

The mechanisms contributing to sarcopenia include reduced satellite cell (myogenic stem
cell) function that is impacted by the environment (niche) of these cells. Satellite cell function …

Skeletal muscle has a remarkable capacity to regenerate by virtue of its resident stem cells
(satellite cells). This capacity declines with aging, although whether this is due to extrinsic …

With an ageing population comes an inevitable increase in the prevalence of age-
associated neurodegenerative diseases, such as amyotrophic lateral sclerosis (ALS), a …

Sarcopenia, the age-related decline in muscle mass and function, derives from multiple
etiological mechanisms. Accumulative research suggests that reactive oxygen species …

Although adult skeletal muscle is composed of fully differentiated fibers, it retains the
capacity to regenerate in response to injury and to modify its contractile and metabolic …