Introduction Genetic data from the Alzheimer's Disease Neuroimaging Initiative (ADNI) have
been crucial in advancing the understanding of Alzheimer's disease (AD) pathophysiology …

Abstract The Alzheimer's Disease Neuroimaging Initiative (ADNI) is an ongoing,
longitudinal, multicenter study designed to develop clinical, imaging, genetic, and …

Over 25 genes are known to affect the risk of developing Alzheimer disease (AD), the most
common neurodegenerative dementia. However, mechanistic insights and improved …

Alzheimer's disease (AD)(MIM: 104300) is a highly heritable disease with great complexity
in its genetic contributors, and represents the most common form of dementia. With the …

Brain imaging genomics is an emerging data science field, where integrated analysis of
brain imaging and genomics data, often combined with other biomarker, clinical, and …

Abstract Introduction The Alzheimer's Disease Neuroimaging Initiative (ADNI) was
established in 2004 to facilitate the development of effective treatments for Alzheimer's …

The discovery of causative genetic mutations in affected family members has historically
dominated our understanding of neurodegenerative diseases such as Alzheimer's disease …

Abstract The Alzheimer's Disease Neuroimaging Initiative (ADNI) is an ongoing,
longitudinal, multicenter study designed to develop clinical, imaging, genetic, and …

Background Alzheimer's disease affects~ 13% of people in the United States 65 years and
older, making it the most common neurodegenerative disorder. Recent work has identified …

Only two genome-wide significant loci associated with longevity have been identified so far,
probably because of insufficient sample sizes of centenarians, whose genomes may harbor …