The future of early cancer detection
A proactive approach to detecting cancer at an early stage can make treatments more
effective, with fewer side effects and improved long-term survival. However, as detection …
effective, with fewer side effects and improved long-term survival. However, as detection …
FLIM as a promising tool for cancer diagnosis and treatment monitoring
Fluorescence lifetime imaging microscopy (FLIM) has been rapidly developed over the past
30 years and widely applied in biomedical engineering. Recent progress in fluorophore …
30 years and widely applied in biomedical engineering. Recent progress in fluorophore …
Fluorescence guided surgery
HL Stewart, DJS Birch - Methods and Applications in …, 2021 - iopscience.iop.org
Fluorescence guided surgery (FGS) is an imaging technique that allows the surgeon to
visualise different structures and types of tissue during a surgical procedure that may not be …
visualise different structures and types of tissue during a surgical procedure that may not be …
Luminescence lifetime imaging of three-dimensional biological objects
ABSTRACT A major focus of current biological studies is to fill the knowledge gaps between
cell, tissue and organism scales. To this end, a wide array of contemporary optical analytical …
cell, tissue and organism scales. To this end, a wide array of contemporary optical analytical …
Machine-learning assisted discrimination of precancerous and cancerous from healthy oral tissue based on multispectral autofluorescence lifetime imaging …
Simple Summary Complete resection of dysplastic and malignant tissue improves overall
survival and delays cancer recurrence in oral cancer patients; however, intraoperative …
survival and delays cancer recurrence in oral cancer patients; however, intraoperative …
Recent advances in point-of-care diagnostics for oral cancer
Early-stage diagnosis is a crucial step in reducing the mortality rate in oral cancer cases.
Point-of-care (POC) devices for oral cancer diagnosis hold great future potential in …
Point-of-care (POC) devices for oral cancer diagnosis hold great future potential in …
Raman imaging and fluorescence lifetime imaging microscopy for diagnosis of cancer state and metabolic monitoring
Simple Summary In spite of significant improvements in diagnosis and treatment options,
cancer treatments still suffer from late detection and patient-specific multidrug resistance …
cancer treatments still suffer from late detection and patient-specific multidrug resistance …
Handheld wide-field fluorescence lifetime imaging system based on a distally mounted SPAD array
AB Matheson, AT Erdogan, C Hopkinson… - Optics …, 2023 - opg.optica.org
In this work a handheld Fluorescent Lifetime IMaging (FLIM) system based on a distally
mounted< 2 mm^ 2 128× 120 single photon avalanche diode (SPAD) array operating over …
mounted< 2 mm^ 2 128× 120 single photon avalanche diode (SPAD) array operating over …
Quantitative multiphoton imaging of cell metabolism, stromal fibers, and keratinization enables label-free discrimination of esophageal squamous cell carcinoma
F Xiang, J Yu, D Jiang, W Hu, R Zhang… - Biomedical Optics …, 2023 - opg.optica.org
Esophageal squamous cell carcinoma (ESCC) features atypical clinical manifestations and
a low 5-year survival rate (< 5% in many developing countries where most of the disease …
a low 5-year survival rate (< 5% in many developing countries where most of the disease …
Oral Potentially Malignant Disorders (OPMD): What is the clinical utility of dysplasia grade?
KPH Pritzker, MR Darling, JTK Hwang… - Expert Review of …, 2021 - Taylor & Francis
Introduction Oral epithelial dysplasia is considered a potential histologic precursor of
subsequent squamous cell cancer. As standard clinical practice, pathologists grade …
subsequent squamous cell cancer. As standard clinical practice, pathologists grade …