Colonic Drug Delivery Systems (CDDS) are especially advantageous for local treatment of
inflammatory bowel diseases (IBD). Site-targeted drug release allows to obtain a high drug …

Background: Parenteral administration of chemotherapeutic drugs, 5-fluorouracil (5-FU) and
leucovorin (LV), is commonly used to treat large bowel carcinomas such as colon cancer …

Despite recent advances in nonsteroidal anti-inflammatory drug (NSAID) formulations, the
design of targeted delivery systems to improve the efficacy and reduce side effects of …

ABSTRACT Colon-Targeted Drug Delivery System (CTDDS) is able to improve local
therapeutic effects in the treatment of colon-specific diseases, such as Crohn's disease …

Magnetic micro-sized mesoporous silica particles were used for the preparation of a gated
material able to release an entrapped cargo in the presence of an azo-reducing agent and …

Normal microflora of human skin and the development of its representatives depending on
the skin pH are considered in this article. It is shown a possibility of using probiotic …

Purpose: The objective of the present study was to develop colon targeted drug delivery
system of Metronidazole using guar gum as the carrier. Methods: Matrix tablets containing …

It is well established that several diseases exhibit circadian behavior, following the relevant
rhythm of the physiological functions of the human body. Their study falls in the fields of …

In oral colon-specific drug delivery systems, the colon has more lymphoma tissue than the
small intestine, which facilitates direct blood absorption, little activity in the brush border …

Meloxicam is a preferential COX 2 inhibitor and a good chemopreventive agent and is used
to prevent colorectal cancer. It's local targeted action on colon makes the treatment more …