Mechanistic Understanding of Candida albicans Biofilm Formation and Approaches for Its Inhibition

T Atriwal, K Azeem, FM Husain, A Hussain… - Frontiers in …, 2021 - frontiersin.org
In recent years, the demand for novel antifungal therapies has increased several-folds due
to its potential to treat severe biofilm-associated infections. Biofilms are made by the sessile …

Intestinal Infection of Candida albicans: Preventing the Formation of Biofilm by C. albicans and Protecting the Intestinal Epithelial Barrier

Z Peng, J Tang - Frontiers in microbiology, 2022 - frontiersin.org
The large mortality and morbidity rate of C. albicans infections is a crucial problem in
medical mycology. Because the generation of biofilms and drug resistance are growing …

Theoretical calculations of molecular descriptors for anticancer activities of 1, 2, 3-triazole-pyrimidine derivatives against gastric cancer cell line (MGC-803): DFT …

RO Oyewole, AK Oyebamiji, B Semire - Heliyon, 2020 - cell.com
Abstracts This work used quantum chemical method via DFT to calculate molecular
descriptors for the development of QSAR model to predict bioactivity (IC 50-50% inhibition …

Diversity of heterocyclic reactants in the click reaction

FA Luzzio - Advances in Heterocyclic Chemistry, 2024 - books.google.com
Diversity of heterocyclic reactants in the click reaction Page 106 CHAPTER THREE Diversity of
heterocyclic reactants in the click reaction Frederick A. Luzzio * Department of Chemistry …

Synthetic transformations of sesquiterpene lactones. Controllable synthesis of 11, 13-dihydroisoalantolactone azides and 13-(1, 2, 3-triazolyl) eudesmanolides based …

SS Patrushev, TV Rybalova, EE Shults - Chemistry of Heterocyclic …, 2021 - Springer
Modification of eudesmane-type lactones isoalantolactone and 4, 15-epoxyisoalantolactone
was carried out at the active methylene group. The reaction of isoalantolactone with …

Design, synthesis, and biological evaluation of novel Tomentosin derivatives in NMDA-induced excitotoxicity

M Zaki, M Loubidi, T Bilgiç, D Birim, M Akssira, T Dagcı… - Pharmaceuticals, 2022 - mdpi.com
N-methyl-D-aspartate (NMDA) receptor stimulation may lead to excitotoxicity, which triggers
neuronal death in brain disorders. In addition to current clinical therapeutic approaches …

Semisynthetic Triazoles as an Approach in the Discovery of Novel Lead Compounds

PAB Morais, CS Francisco, H de Paula… - Current Organic …, 2021 - ingentaconnect.com
Historically, medicinal chemistry has been concerned with the approach of organic
chemistry for new drug synthesis. Considering the fruitful collections of new molecular …

Синтетические трансформации сесквитерпеновых лактонов. Контролируемый синтез азидов 11, 13-дигидроизоалантолактона и 13-(1, 2, 3-триазолил) …

ТВ Рыбалова, ЭЭ Шульц - Chemistry of Heterocyclic Compounds, 2021 - osi131.osi.lv
Осуществлена модификация лактонов эудесманового типа–изоалантолактона и 4, 15-
эпоксиизоалантолактона–по активной метиленовой группе. Взаимодействие …

[PDF][PDF] Programa de Pós-Graduação em Agroquímica Centro de Ciências Exatas, Naturais e da Saúde

LCDEF FERREIRA, SDEDT DO ADAMANTANO - repositorio.ufes.br
RESUMO A pimenta-do-reino é uma especiaria amplamente utilizada desde a antiguidade
e é considerada um produto que agrega valor para a agroindústria. O estado do Espírito …

Etude de la réactivité régio-stéréosélective de la nitration, de l'acylation, de l'époxydation et de la cycloaddition [3+ 2] par la théorie de la fonctionnelle de la densité

S ELHAMIDI - 2021 - toubkal.imist.ma
Dans ce travail, nous avons réalisé une approche théorique de la réactivité chimique de
quelques réactions modèles de substitution électrophile aromatique, d'époxydation …