Insects are infected by a wide array of viruses some of which are insect restricted and
pathogenic, and some of which are transmitted by biting insects to vertebrates. The medical …

The advent of microRNA has potentially uncovered a new level of complexity to be
considered for every biological process. Through the modulation of transcription and …

MicroRNAs usually interact with 3′ noncoding regions (3′ NCRs) of target mRNAs
leading to downregulation of mRNA expression. In contrast, liver-specific microRNA miR …

Hepatitis C virus subverts liver-specific microRNA, miR-122, to upregulate viral RNA
abundance in both infected cultured cells and in the liver of infected chimpanzees. These …

Over the past few decades, si RNA and mi RNA have attracted a great deal of attention from
researchers and clinicians. These molecules have been extensively studied from the …

Systemic iron homeostasis is mainly controlled by the liver through synthesis of the peptide
hormone hepcidin (encoded by Hamp), the key regulator of duodenal iron absorption and …

MicroRNAs are a recently discovered new class of important endogenous regulators of gene
function. Aberrant regulation of microRNAs has been linked to various human diseases …

Background Cellular miRNAs play an important role in the regulation of gene expression in
eukaryotes. Recently, miRNAs have also been shown to be able to target and inhibit viral …

MicroRNAs (miRNAs) are an important class of non-coding small RNAs that possess a large
range of biological activities in a variety of organisms and are linked to human diseases …

Since the elaboration of the central dogma of molecular biology, our understanding of cell
function and genome action has benefited from many radical discoveries. The discoveries …