Practical algorithm for stochastic optimal control problem about microbial fermentation in batch culture

L Wang, J Yuan, C Wu, X Wang - Optimization Letters, 2019 - Springer
How to add glycerol to maximize production of 1, 3-propanediol (1, 3-PD) is a critical
problem in process control of microbial fermentation. Most of the existing works are focusing …

[HTML][HTML] Modelling and parameter identification for a nonlinear time-delay system in microbial batch fermentation

C Liu - Applied Mathematical Modelling, 2013 - Elsevier
Mathematical modelling and parameter identification of a microbial batch fermentation
process is considered in this paper. In view of the existence of time delays, a nonlinear time …

Optimizing design for continuous conversion of glycerol to 1, 3-propanediol using discrete-valued optimal control

J Wang, X Zhang, J Ye, J Wang, E Feng - Journal of Process Control, 2021 - Elsevier
This paper focuses on modeling and optimizing design for continuous conversion of glycerol
to 1, 3-propanediol by Klebsiella pneumoniae, wherein dilution rate of the feed medium is …

Robust optimal control of a microbial batch culture process

G Cheng, L Wang, R Loxton, Q Lin - Journal of Optimization Theory and …, 2015 - Springer
This paper considers the microbial batch culture process for producing 1, 3-propanediol (1,
3-PD) via glycerol fermentation. Our goal was to design an optimal control scheme for this …

Robust identification of enzymatic nonlinear dynamical systems for 1, 3-propanediol transport mechanisms in microbial batch culture

J Yuan, X Zhu, X Zhang, H Yin, E Feng, Z Xiu - Applied Mathematics and …, 2014 - Elsevier
In this paper, in view of glycerol bioconversion to 1, 3-propanediol (1, 3-PD) by Klebsiella
pneumoniae (K. pneumoniae), we study an enzyme-catalytic nonlinear dynamic system with …

Modeling and multi-objective optimal state-dependent control of a continuous double-bioreactor in series fermentation

J Wang, F Zhao, J Wang, A Li - Mathematics and Computers in Simulation, 2025 - Elsevier
This paper models a continuous double-bioreactor in series fermentation of glycerol to 1, 3-
propanediol by a nonlinear dynamic system and formulates its process control by a multi …

Modelling and pathway identification involving the transport mechanism of a complex metabolic system in batch culture

J Yuan, X Zhang, X Zhu, E Feng, H Yin, Z Xiu - … in Nonlinear Science and …, 2014 - Elsevier
The bio-dissimilation of glycerol to 1, 3-propanediol (1, 3-PD) by Klebsiella pneumoniae (K.
pneumoniae) can be characterized by a complex metabolic system of interactions among …

[HTML][HTML] Modeling and identification of a nonlinear hybrid dynamical system in batch fermentation of glycerol

J Wang, J Ye, E Feng, H Yin, Z Xiu - Mathematical and Computer Modelling, 2011 - Elsevier
A nonlinear hybrid dynamical system is established to describe the batch culture of glycerol
to 1, 3-propanediol (1, 3-PD) by Klebsiella pneumoniae (K. pneumoniae), in which glycerol …

Robust parameter identification using parallel global optimization for a batch nonlinear enzyme-catalytic time-delayed process presenting metabolic discontinuities

J Yuan, Y Zhang, J Ye, J Xie, KL Teo, X Zhu… - Applied Mathematical …, 2017 - Elsevier
In this paper, a nonlinear enzyme-catalytic time-delayed switched dynamical system is
considered to describe batch culture of glycerol bioconversion to 1, 3-propanediol induced …

Modeling nonlinear stochastic kinetic system and stochastic optimal control of microbial bioconversion process in batch culture

L Wang, E Feng, Z Xiu - Nonlinear Analysis: Modelling and Control, 2013 - zurnalai.vu.lt
In this paper, we analyze a stochastic model representing batch fermentation in the process
of glycerol bio-dissimilation to 1, 3-propanediol by klebsiella pneumoniae. The stochasticity …