Mayer–Rokitansky–Küster–Hauser (MRKH) syndrome, also referred to as Müllerian
agenesis, is the second most common cause of primary amenorrhea. It is characterized by …

Evidence is accumulating that environmental chemicals (ECs) including endocrine-
disrupting compounds (EDCs) can alter female reproductive development, fertility and onset …

Zusammenfassung Das Mayer-Rokitansky-Küster-Hauser (MRKH) Syndrom [MIM 277000]
ist durch einen fehlenden Uterus und eine fehlende Vagina bei phänotypisch unauffälligen …

Wingless-type mouse mammary tumor virus integration site (WNT) signaling molecules are
locally secreted glycoproteins that play important role in regulation of ovarian follicle …

The process of sexual differentiation is central for reproduction of almost all metazoan, and
therefore, for maintenance of practically all multicellular organisms. In sex development, we …

Rationale: Vascular smooth muscle cell (VSMC) proliferation causes intimal thickening in
atherosclerosis and restenosis. Previously, we demonstrated that Wnt/β-catenin signaling …

Uterine leiomyomas (ULs) are benign tumors that are a major burden to women's health. A
genome-wide association study on 15,453 UL cases and 392,628 controls was performed …

There is emerging evidence that early uterine development in humans is an important
determinant of conditions such as ontogenetic progesterone resistance, menstrual …

Our understanding of avian sex determination and gonadal development is derived primarily
from the studies in the chicken. Analysis of gynandromorphic chickens and experimental …

The Dmrt (Doublesex and Mab-3 related transcription factor) gene family is a class of crucial
transcription factors characterized by a conserved DM domain related to sex determination …