Viewing metabolism through the lens of exercise biology has proven an accessible and
practical strategy to gain new insights into local and systemic metabolic regulation. Recent …

Human skeletal muscle demonstrates remarkable plasticity, adapting to numerous external
stimuli including the habitual level of contractile loading. Accordingly, muscle function and …

Exercise, in the form of endurance or resistance training, leads to specific molecular and
cellular adaptions not only in skeletal muscles, but also in many other organs such as the …

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Axonal transport ensures long-range delivery of essential cargoes between proximal and
distal compartments, and is needed for neuronal development, function, and survival …

Skeletal muscle health and function are important determinants of systemic metabolic
homeostasis and organism-wide responses, including disease outcome. While it is well …

Low skeletal muscle mass is associated with cognitive impairment and dementia in older
adults. This review describes the possible underlying pathophysiological mechanisms …

In muscular dystrophies, muscle fibers loose integrity and die, causing significant suffering
and premature death. Strikingly, the extraocular muscles (EOMs) are spared, functioning …

The skeletal muscle is a highly heterogeneous tissue comprised of different fiber types with
varying contractile and metabolic properties. The complexity in the analysis of skeletal …

MyoD is a skeletal muscle-specifically expressed transcription factor and plays a critical role
in regulating myogenesis during muscle development and regeneration. However, whether …