The treatment of Cushing's disease

R Pivonello, M De Leo, A Cozzolino… - Endocrine …, 2015 - academic.oup.com
Abstract Cushing's disease (CD), or pituitary-dependent Cushing's syndrome, is a severe
endocrine disease caused by a corticotroph pituitary tumor and associated with increased …

The pathogenetic role of cortisol in the metabolic syndrome: a hypothesis

P Anagnostis, VG Athyros, K Tziomalos… - The Journal of …, 2009 - academic.oup.com
Context: The metabolic syndrome (MetS) is a cluster of metabolic abnormalities that
increase the risk for type 2 diabetes mellitus and vascular disease. The common …

Metabolic comorbidities in Cushing's syndrome

F Ferrau, M Korbonits - European Journal of Endocrinology, 2015 - academic.oup.com
Cushing's syndrome (CS) patients have increased mortality primarily due to cardiovascular
events induced by glucocorticoid (GC) excess-related severe metabolic changes. Glucose …

Cushing's syndrome: Overview of clinical presentation, diagnostic tools and complications

M Barbot, M Zilio, C Scaroni - … practice & research Clinical endocrinology & …, 2020 - Elsevier
Cushing's syndrome (CS) is a severe condition that results from chronic exposure to
elevated circulating cortisol levels; it is a rare but potentially life-threating condition …

Progressively increased patterns of subclinical cortisol hypersecretion in adrenal incidentalomas differently predict major metabolic and cardiovascular outcomes: a …

G Di Dalmazi, V Vicennati, E Rinaldi… - European Journal of …, 2012 - academic.oup.com
Abstract Background Subclinical Cushing's syndrome (SCS) is defined as alterations in
hypothalamic–pituitary–adrenal axis without classic signs/symptoms of glucocorticoid …

[HTML][HTML] Systematic review on the effect of glucocorticoid use on procoagulant, anti‐coagulant and fibrinolytic factors

B van Zaane, E Nur, A Squizzato, VEA Gerdes… - Journal of Thrombosis …, 2010 - Elsevier
Background: Whether glucocorticoid use contributes to a hypercoagulable state, and
thereby enhances the thrombotic risk, is controversial. Objective: We aimed to examine the …

The hypertension of Cushing's syndrome: controversies in the pathophysiology and focus on cardiovascular complications

AM Isidori, C Graziadio, RM Paragliola… - Journal of …, 2015 - journals.lww.com
Cushing's syndrome is associated with increased mortality, mainly due to cardiovascular
complications, which are sustained by the common development of systemic arterial …

Adverse effects of glucocorticoids: coagulopathy

MCA Coelho, CV Santos, LV Neto… - European Journal of …, 2015 - academic.oup.com
Hypercortisolism is associated with various systemic manifestations, including central
obesity, arterial hypertension, glucose intolerance/diabetes mellitus, dyslipidemia …

Management of endocrine disease: cardiovascular risk assessment, thromboembolism, and infection prevention in Cushing's syndrome: a practical approach

EV Varlamov, F Langlois, G Vila… - European journal of …, 2021 - academic.oup.com
Cushing's syndrome (CS) is associated with increased mortality that is driven by
cardiovascular, thromboembolic, and infection complications. Although these events are …

Blood coagulation and fibrinolysis in patients with Cushing's syndrome: increased plasminogen activator inhibitor-1, decreased tissue factor pathway inhibitor, and …

C Erem, I Nuhoglu, M Yilmaz, M Kocak… - Journal of …, 2009 - Springer
Background and objectives: Cushing's syndrome (CS) is associated with an increased
cardiovascular mortality and morbidity. Chronic endogenous and exogenous …