The developing brain in utero and during the first years of life is highly vulnerable to
environmental influences. Experiences occurring during this period permanently modify …

The study of depression in mothers in relation to transmission of risk for the development of
psychopathology in their children relies on solid foundations in the understanding of …

The assumption that early stress leads to dysregulation and impairment is widespread in
developmental science and informs prevailing models (eg, toxic stress). An alternative …

Importance Exposure to early-life adversity alters the structural development of key brain
regions underlying neurodevelopmental impairments. The association between prenatal …

Maternal mental illness can have a devastating effect during the perinatal period, and has a
profound impact on the care that the baby receives and on the relationships that the baby …

According to several theories, people differ in their sensitivity to environmental influences
with some more susceptible than others to both supportive and adverse contextual …

Early-life adversity (ELA) exposure is suggested to accelerate development. However, the
influence of ELA on neurodevelopmental trajectories has not been assessed directly but …

Objective Prenatal maternal symptoms of depression and anxiety are associated with an
increased risk for child socioemotional and behavioral difficulties, supporting the fetal origins …

Inhibitory control deficits are prevalent in multiple neuropsychiatric conditions. The
communication-as well as the connectivity-between corticolimbic regions of the brain are …

Early-life adversity affects long-term health outcomes but there is considerable
interindividual variability in susceptibility to environmental influences. We proposed that …