Post-translational modifications (PTMs) greatly increase protein diversity and functionality.
To help the plant research community interpret the ever-increasing number of reported …

Though proteases were long regarded as nonspecific degradative enzymes, over time, it
was recognized that they also hydrolyze peptide bonds very specifically with a limited …

We have developed a one-step method to isolate protein C-terminal peptides from V8
protease-digested proteins by metal oxide-based ligand-exchange (MOLEX) …

Liquid chromatography-mass spectrometry (LC-MS) is the method of choice for high-
throughput proteomic research. Limited by the peak capacity, the separation performance of …

Protein N‐and C‐termini have specific biochemical properties and functions. They play vital
roles in various biological processes, such as protein stability and localization. In addition …

Protein termini play pivotal roles in various biological processes. Although several
terminomic strategies have been proposed for the analysis of protein N-termini or protein C …

The determination of protein C-termini is of great significance for protein function annotation
and proteolysis research. However, the progress of C-terminomics is still far behind its …

Protein methylation as one of the most important post-translational modifications has been
under the spotlight due to its essential role in many biological processes. Development of …

Protein termini are generally associated with protein stability. Taking advantage of charge
state differences between terminal peptides and internal peptides, we developed a new …

蛋白质的磷酸化在细胞信号传导和疾病发生发展中起着重要作用, 但磷酸化的动态变化和低丰度
的特点使得对其直接分析有着较大的困难。 为了解决磷酸化肽难离子化 …