Biomedical applications of multifunctional polymeric nanocarriers: a review of current literature

A Karabasz, M Bzowska… - International Journal of …, 2020 - Taylor & Francis
Polymeric nanomaterials have become a prominent area of research in the field of drug
delivery. Their application in nanomedicine can improve bioavailability, pharmacokinetics …

PEGylated and functionalized polylactide-based nanocapsules: An overview

MA de Oliveira, RS Araújo, VCF Mosqueira - International Journal of …, 2023 - Elsevier
Polymeric nanocapsules (NC) are versatile mixed vesicular nanocarriers, generally
containing a lipid core with a polymeric wall. They have been first developed over four …

[HTML][HTML] Lipid-based nanocarriers co-loaded with artemether and triglycerides of docosahexaenoic acid: Effects on human breast cancer cells

EG Lanna, RP Siqueira, MGC Machado… - Biomedicine & …, 2021 - Elsevier
Artemether (ART) was combined with triglyceride of docosahexaenoic acid (DHA) as the
lipid-core in nanoemulsions (NE), nanostructured lipid carriers (NLC), and PEG-PLA …

Artemether-loaded zein nanoparticles: An innovative intravenous dosage form for the management of severe malaria

Y Boateng-Marfo, Y Dong, WK Ng, HS Lin - International Journal of …, 2021 - mdpi.com
Artemether, an artemisinin derivative, is used in the management of life-threatening severe
malaria. This study aimed to develop an intravenous dosage form of artemether using …

Mechanisms of interaction of biodegradable polyester nanocapsules with non-phagocytic cells

IC Trindade, G Pound-Lana, DGS Pereira… - European Journal of …, 2018 - Elsevier
The interaction of polymer nanocapsules (NC) prepared from four biodegradable polyesters
with variable polymer hydrophobicity (PCL, PLA, PLGA and PLA-PEG) was investigated in …

Nano-facilitated drug delivery strategies in the treatment of plasmodium infection

N Puttappa, RS Kumar, G Kuppusamy… - Acta tropica, 2019 - Elsevier
Malaria, one of the major infectious disease-causing sizeable morbidity, mortality and
economic loss worldwide. The main drawback for the failure to eradicate malaria is the …

Mechanisms of artemether toxicity on single cardiomyocytes and protective effect of nanoencapsulation

AC Moreira Souza, A Grabe‐Guimarães… - British Journal of …, 2020 - Wiley Online Library
Background and Purpose The artemisinin derivative, artemether, has antimalarial activity
with potential neurotoxic and cardiotoxic effects. Artemether in nanocapsules (NC‐ATM) is …

Polyester nanocapsules for intravenous delivery of artemether: Formulation development, antimalarial efficacy, and cardioprotective effects in vivo

AT Vidal-Diniz, HN Guimarães, GM Garcia, ÉM Braga… - Polymers, 2022 - mdpi.com
Artemether (ATM) is an effective antimalarial drug that also has a short half-life in the blood.
Furthermore, ATM is also cardiotoxic and is associated with pro-arrhythmogenic risks. We …

Nanotherapeutics against malaria: A decade of advancements in experimental models

Y Avalos‐Padilla… - Wiley Interdisciplinary …, 2024 - Wiley Online Library
Malaria, caused by different species of protists of the genus Plasmodium, remains among
the most common causes of death due to parasitic diseases worldwide, mainly for children …

Nanotechnology based drug delivery systems for malaria

S Keleş, J Alakbarli, B Akgül, M Baghirova… - International Journal of …, 2024 - Elsevier
Malaria, caused by Plasmodium parasites transmitted through Anopheles mosquitoes,
remains a global health burden, particularly in tropical regions. The most lethal species …