Occurrence and spatial distribution of pharmaceuticals and personal care products (PPCPs) in the aquatic environment, their characteristics, and adopted legislations

HB Hawash, AA Moneer, AA Galhoum… - Journal of Water …, 2023 - Elsevier
Pharmaceuticals and personal care products (PPCPs) residues are known to occur widely in
the aquatic environments of industrialized and developing countries. Considerable progress …

Occurrence of the antiepileptic carbamazepine in water and bivalves from marine environments: A review

 Almeida, AMVM Soares, VI Esteves… - Environmental Toxicology …, 2021 - Elsevier
A vast literature has already demonstrated that pharmaceutical drugs exert negative impacts
on aquatic organisms but data is sparse on the occurrence of these contaminants in marine …

[HTML][HTML] Intranasal administration of carbamazepine-loaded carboxymethyl chitosan nanoparticles for drug delivery to the brain

S Liu, S Yang, PC Ho - asian journal of pharmaceutical sciences, 2018 - Elsevier
Epilepsy is considered as a common and diverse set of chronic neurological disorders and
its symptoms can be controlled by antiepileptic drugs (AEDs). The presence of p …

[HTML][HTML] High-throughput multi-residue quantification of contaminants of emerging concern in wastewaters enabled using direct injection liquid chromatography …

KT Ng, H Rapp-Wright, M Egli, A Hartmann… - Journal of hazardous …, 2020 - Elsevier
A rapid quantitative method for 135 contaminants of emerging concern (CECs) in untreated
wastewater enabled with direct injection liquid chromatography-tandem mass spectrometry …

[HTML][HTML] Carbamazepine, venlafaxine, tramadol, and their main metabolites: Toxicological effects on zebrafish embryos and larvae

P Rodrigues, L Guimarães, AP Carvalho… - Journal of Hazardous …, 2023 - Elsevier
Pharmaceutical compounds and their metabolites are found in natural and wastewater.
However, investigation of their toxic effects on aquatic animals has been neglected …

Therapeutic potential of an anti-high mobility group box-1 monoclonal antibody in epilepsy

J Zhao, Y Wang, C Xu, K Liu, Y Wang, L Chen… - Brain, behavior, and …, 2017 - Elsevier
Brain inflammation is a major factor in epilepsy, and the high mobility group box-1 (HMGB1)
protein is known to contribute significantly to the generation of seizures. Here, we …

Pharmacokinetic drug–drug interactions among antiepileptic drugs, including CBD, drugs used to treat COVID-19 and nutrients

M Karaźniewicz-Łada, AK Główka, AA Mikulska… - International Journal of …, 2021 - mdpi.com
Anti-epileptic drugs (AEDs) are an important group of drugs of several generations, ranging
from the oldest phenobarbital (1912) to the most recent cenobamate (2019). Cannabidiol …

Toxic effects of four emerging pollutants on cardiac performance and associated physiological parameters of the thick-shell mussel (Mytilus coruscus)

Y Yu, D Tong, Y Yu, D Tian, W Zhou, X Zhang… - Environmental …, 2023 - Elsevier
Robust cardiac performance is critical for the health and even survival of an animal;
however, it is sensitive to environmental stressors. At present, little is known about the …

Carbamazepine adverse drug reactions

I Fricke-Galindo, A LLerena, H Jung-Cook… - Expert review of …, 2018 - Taylor & Francis
Introduction: Carbamazepine (CBZ) is used for the treatment of epilepsy and other
neurological and psychiatric disorders. The occurrence of adverse reactions (ADRs) to CBZ …

Effects of common antiepileptic drugs on teleost fishes

A Salahinejad, D Meuthen, A Attaran… - Science of The Total …, 2023 - Elsevier
Antiepileptic drugs (AEDs) are globally prescribed to treat epilepsy and many other
psychiatric disorders in humans. Their high consumption, low metabolic rate in the human …