Abstract Development of a cancer is a multistep process and six major hallmarks of cancer
that are known to control malignant transformation have been described. Anticancer drug …

Aberrant protein phosphorylation is one of the hallmarks of cancer cells, and in many cases
a prerequisite to sustain tumor development and progression. Like protein kinases, protein …

Background: Bevacizumab-based regimens are used as standard treatments for colorectal
cancer. Unfortunately, there are no established predictive markers for bevacizumab …

Background A promising arsenal of histone deacetylase (HDAC)-targeted treatment has
emerged in the past decade, as the abnormal targeting or retention of HDACs to DNA …

Gastric carcinoma is highly prevalent throughout the world. Understanding the pathogenesis
of this disease will benefit diagnosis and resolution. Studies show that miRNAs are involved …

Cetuximab is the sole anti-EGFR monoclonal antibody that is FDA approved to treat head
and neck squamous cell carcinoma (HNSCC). However, no predictive biomarkers of …

Vimentin, a type III intermediate filament protein, is found in most cells along with
microfilaments and microtubules. It has been shown that the head domain folds back to …

MicroRNAs (miRNAs) are small noncoding RNAs that act as fine-tuners of the post-
transcriptional control of protein-coding or noncoding RNAs by repressing translation or …

The decellularization of tissues or organs provides an efficient strategy for preparing
functional scaffolds for tissue engineering. The microstructures of native extracellular …

Squamous cell carcinoma (SCC) of pancreas is a rare histotype of pancreatic ductal
carcinoma which is distinct from pancreatic adenocarcinoma (AC). Although there are …