Key Clinical Points Depression in the Primary Care Setting Screening for depression and
suicidal thinking and behavior is important in the primary care setting. Distinguishing …

Background: The Canadian Network for Mood and Anxiety Treatments (CANMAT)
conducted a revision of the 2009 guidelines by updating the evidence and …

The concept of alliance reflects the collaborative relationship between a clinician and a
patient, defined as consisting of three elements: a) the agreement on the goals of treatment; …

British Psychology Society Textbook of the Year 2020 Why do people who are more socially
connected live longer and have better health than those who are socially isolated? Why are …

Depression is widely acknowledged to be a heterogeneous entity, and the need to further
characterize the individual patient who has received this diagnosis in order to personalize …

Depression is one of the leading causes of disability, and, if left unmanaged, it can increase
the risk for suicide. The evidence base on the determinants of depression is fragmented …

Mental health researchers and clinicians have long sought answers to the question “What
works for whom?” The goal of precision medicine is to provide evidence-based answers to …

Depression is a highly prevalent risk factor for incident coronary heart disease (CHD) and for
cardiovascular morbidity and mortality in patients with established CHD. Several biological …

Objectives To characterize individual participant level response distributions to acute
monotherapy for major depressive disorder in randomized, placebo controlled trials …

Inflammatory cytokines are commonly elevated in acute depression and are associated with
resistance to monoaminergic treatment. To examine the potential role of cytokines in the …