Alzheimer's disease (AD) is the most common cause of dementia worldwide, and its
prevalence is rapidly increasing due to extended lifespans. Among the increasing number of …

The prevalence of Alzheimer's disease (AD) continues to rise due to the increasing aging
population. Among the various genetic factors associated with AD, apolipoprotein E (ApoE) …

Alzheimer's disease (AD) is a complex and progressive disease, which affects millions of
people around the world. Despite the many efforts over the years to find efficient …

Background The association between omega-3 (ω-3) PUFAs and cognition, brain imaging
and biomarkers is still not fully established. Objectives The aim was to analyze the cross …

Abstract Background Lead (Pb), an environmental neurotoxicant, is known to induce
cognitive impairment. Neuroinflammation and oxidative stress in the brain tissue are …

Docosahexaenoic acid [22: 6 (n-3), DHA], a polyunsaturated fatty acid, has an important role
in regulating neuronal functions and in normal brain development. Dysregulated brain DHA …

The metabolism of docosahexaenoic acid (DHA), an omega-3 fatty acid, is different in
carriers of APOE4, the main genetic risk factor for late-onset Alzheimer's disease. The brain …

INTRODUCTION Fatty acids (FAs) are the building blocks of complex lipids and signaling
compounds; the role of the lipidome fatty acid profile (LFA) in AD progression remains …

Background: We investigated systemic biochemical changes in Alzheimer's disease (AD) by
investigating the relationship between circulating plasma metabolites and both clinical and …

Background We profiled circulating plasma metabolites to identify systemic biochemical
changes in clinical and biomarker-assisted diagnosis of Alzheimer's disease (AD). Methods …