The therapeutic targeting of extracellular proteins is becoming hugely attractive in light of
evidence implicating the tumour microenvironment as pivotal in all aspects of tumour …

Glaucoma, a diverse group of eye disorders that results in the degeneration of retinal
ganglion cells, is the world's leading cause of irreversible blindness. Apart from age and …

Exfoliation syndrome (XFS) is the most common known risk factor for secondary glaucoma
and a major cause of blindness worldwide. Variants in two genes, LOXL1 and CACNA1A …

Exfoliation syndrome (XFS) is a common age-related disorder that leads to deposition of
extracellular fibrillar material throughout the body. The most recognized disease …

Glaucoma, the world's leading cause of irreversible blindness, is a complex disease, with
differential presentation as well as ethnic and geographic disparities. The multifactorial …

Pseudoexfoliation syndrome (PXS) is a systemic condition with eye manifestations. In the
eye, pseudoexfoliation material deposits on various structures of the anterior segment. The …

Glaucoma, a leading cause of blindness worldwide, is characterized by progressive optic
nerve damage, usually associated with intraocular pressure. Although the clinical …

Glaucoma is a family of diseases whose pathology is defined by the progressive loss of
retinal ganglion cells. Clinically, glaucoma presents as a distinctive optic neuropathy with …

Exfoliation syndrome (XFS) is the most common recognizable cause of open-angle
glaucoma worldwide. To better understand the etiology of XFS, we conducted a genome …

The authors indicate four key issues which, in their opinion, represent the most stimulating
challenges in the field of glaucoma today, and describe the present approaches and the …