The vascular endothelium, a monolayer of endothelial cells (EC), constitutes the inner
cellular lining of arteries, veins and capillaries and therefore is in direct contact with the …

Numerous studies have demonstrated that endothelial cells are capable of undergoing
endothelial to mesenchymal transition (EndMT), a newly recognized type of cellular …

Background: Endothelial cells (ECs) display considerable functional heterogeneity
depending on the vessel and tissue in which they are located. Whereas these functional …

In addition to the roles of endothelial cells (ECs) in physiological processes, ECs actively
participate in both innate and adaptive immune responses. We previously reported that, in …

Hemostasis encompasses a set of tightly regulated processes that govern blood clotting,
platelet activation, and vascular repair. Upon vascular injury, the hemostatic system initiates …

Coagulation is a dynamic process and the understanding of the blood coagulation system
has evolved over the recent years in anaesthetic practice. Although the traditional …

Since the emergence of regenerative medicine and tissue engineering more than half a
century ago, one obstacle has persisted: the in vitro creation of large-scale vascular tissue (> …

Alterations of endothelial cells and the vasculature play a central role in the pathogenesis of
a broad spectrum of the most dreadful of human diseases, as endothelial cells have the key …

Background: The cells that form the arterial wall contribute to multiple vascular diseases.
The extent of cellular heterogeneity within these populations has not been fully …

Brain capillary endothelial cells form the blood-brain barrier (BBB), which is covered with
basement membranes and is also surrounded by pericytes and astrocyte end-feet in the …