Combined cellular and humoral host immune response determine the clinical course of a
viral infection and effectiveness of vaccination, but currently the cellular immune response …

Simple Summary Immunotherapy enhances the immune response against cancer and is
potentially curative. Unfortunately, few patients with breast cancer benefit from this therapy. It …

The complex interplay between kinases and transcription factors is fundamental to the
burgeoning field of immunometabolism, which investigates the intersection of cellular …

The Notch signal transduction pathway is pivotal for various physiological processes
including immune responses, and has been implicated in the pathogenesis of many …

The present invention relates to a method for determining the immunosuppressive state of a
subject having a tumor by analyzing the Notch cellular signaling pathways activity. The …