As early and effective antiretroviral therapy has become more widespread, HIV has
transitioned from a progressive, fatal disease to a chronic, manageable disease marked by …

Over the last 3 decades there have been substantial improvements in treatments aimed at
reducing cardiovascular (CV) events. As these treatments have been developed, there have …

Background: Immune checkpoint inhibitors (ICIs) treat an expanding range of cancers.
Consistent basic data suggest that these same checkpoints are critical negative regulators of …

Aims The use of biologic therapy has increased over the past decade well beyond primary
autoimmune diseases. Indeed, a recent trial using an anti-IL-1beta antibody reduced second …

Advances in atherosclerosis imaging technology and research have provided a range of
diagnostic tools to characterize high-risk plaque in vivo; however, these important vascular …

HIV infection has transitioned from an acute, fatal disease to a chronic one managed by
antiretroviral therapy. Thus, the aging population of people living with HIV (PLWH) continues …

Antiretroviral therapy has largely transformed HIV infection into a chronic disease condition.
As such, physicians and other providers caring for individuals living with HIV infection need …

Inflammation is thought to play an important role in the pathogenesis of vascular diseases.
Lipoprotein‐associated phospholipase A2 (Lp‐PLA2) mediates vascular inflammation …

Cardiac computed tomography (CT) was initially developed as a non-invasive diagnostic
tool to detect and quantify coronary stenosis. Thanks to the rapid technological …

Cardiovascular disease is one of the leading causes of morbidity and mortality in people
living with HIV. Several epidemiological studies have shown an increased risk of myocardial …