Recent progress in RNA biology has broadened the scope of therapeutic targets of RNA
drugs for cancer therapy. However, RNA drugs, typically small interfering RNAs (siRNAs) …

This review summarizes the current understanding of adsorption of polyelectrolytes to
oppositely charged solid substrates, the resulting interaction forces between such …

Polymeric materials have been extensively developed as a delivery vehicle for nucleic acids
over the past two decades. Many previous studies have demonstrated that synthetic delivery …

Linear PEI is a cationic polymer commonly used for complexing DNA into nanoparticles for
cell-transfection and gene-therapy applications. The polymer has closely-spaced amines …

Supramolecular self-assembly offers a powerful strategy to produce high-performance,
stimuli-responsive nanomaterials. However, lack of molecular understanding of stimulated …

A series of the N-substituted polyaspartamides possessing repeating aminoethylene units in
the side chain was prepared in this study to identify polyplexes with effective endosomal …

Polycations having a high buffering capacity in the endosomal pH range, such as
polyethylenimine (PEI), are known to be efficient at delivering nucleic acids by overcoming …

The success of polyethyleneimine (PEI) as a nonviral-based gene delivery vector has been
attributed to its proton buffering capacity. Despite the great interest in PEI for its use in …

The theoretical and rational modelling of self-assembly processes is far less developed than
the flourishing structural characterization of the resulting sophisticated and aesthetically …

Tunable gating polymeric nanostructured membrane with excellent water permeability and
precise molecular separation is highly advantageous for smart nanofiltration application …