Tumor necrosis factor (TNF) is tremendously important for mammalian immunity and cellular
homeostasis. The role of TNF as a master regulator in balancing cell survival, apoptosis and …

Metabolic rewiring and the consequent production of reactive oxygen species (ROS) are
necessary to promote tumorigenesis. At the nexus of these cellular processes is the aberrant …

Alzheimer's disease (AD) is the foremost type of dementia that afflicts considerable morbidity
and mortality in aged population. Several transcription molecules, pathways, and molecular …

Lentinan (LNT) has been reported to have a wide range of functions, including anti-
inflammatory, antioxidant and anticancer properties. LNT may provide a protective effect in …

Redox-dependent processes influence most cellular functions, such as differentiation,
proliferation, and apoptosis. Mitochondria are at the center of these processes, as …

Marine secondary metabolites are a promising source of unexploited drugs that have a wide
structural diversity and have shown a variety of biological activities. These compounds are …

Mitochondria, the cell's major energy producers, also act as signaling hubs, interacting with
other organelles both directly and indirectly. Despite having its own circular genome, the …

Unilateral ureteral obstruction (UUO) is an experimental rodent model that mimics renal
fibrosis associated with obstructive nephropathy in an accelerated manner. After UUO, the …

Using high-throughput screening we identified small molecules that suppress superoxide
and/or H 2 O 2 production during reverse electron transport through mitochondrial …

Environmental exposure to silica nanoparticles (SiNPs) is inevitable due to their widespread
application in industrial, commercial, and biomedical fields. In recent years, most …