MAFLD: How is it different from NAFLD?

C Gofton, Y Upendran, MH Zheng… - Clinical and molecular …, 2022 - pmc.ncbi.nlm.nih.gov
“Metabolic dysfunction-associated fatty liver disease (MAFLD)” is the term suggested in
2020 to refer to fatty liver disease related to systemic metabolic dysregulation. The name …

Intestinal barrier and permeability in health, obesity and NAFLD

P Portincasa, L Bonfrate, M Khalil, MD Angelis… - Biomedicines, 2021 - mdpi.com
The largest surface of the human body exposed to the external environment is the gut. At this
level, the intestinal barrier includes luminal microbes, the mucin layer, gastrointestinal …

MAFLD enhances clinical practice for liver disease in the Asia-Pacific region

T Kawaguchi, T Tsutsumi, D Nakano… - Clinical and …, 2021 - pmc.ncbi.nlm.nih.gov
Fatty liver is now a major cause of liver disease in the Asia-Pacific region. Liver diseases in
this region have distinctive characteristics. First, fatty liver is frequently observed in …

[HTML][HTML] Steatotic liver disease, MASLD and risk of chronic kidney disease

J Bilson, A Mantovani, CD Byrne, G Targher - Diabetes & metabolism, 2024 - Elsevier
With the rising tide of fatty liver disease related to metabolic dysfunction worldwide, the
association of this common liver disease with chronic kidney disease (CKD) has become …

Metabolic dysfunction-associated fatty liver disease: a year in review

J Alharthi, A Gastaldelli, IH Cua… - Current Opinion in …, 2022 - journals.lww.com
The transformation in name and definition from NAFLD to MAFLD represents an important
milestone, which indicates significant tangible progress towards a more inclusive, equitable …

[HTML][HTML] Nonalcoholic fatty liver disease versus metabolic-associated fatty liver disease: Prevalence, outcomes and implications of a change in name

CH Ng, DQ Huang, MH Nguyen - Clinical and Molecular …, 2022 - ncbi.nlm.nih.gov
Nonalcoholic fatty liver disease (NAFLD) affects about a third of the world's adult population
and is a major public health concern. NAFLD is defined by the presence of hepatic steatosis …

Metabolic associated fatty liver disease increases the risk of systemic complications and mortality. A meta-analysis and systematic review of 12 620 736 individuals

J Quek, CH Ng, ASP Tang, N Chew, M Chan… - Endocrine Practice, 2022 - Elsevier
Objective The recent introduction of the term metabolic associated fatty liver disease
(MAFLD) sought to reclassify nonalcoholic fatty liver disease (NAFLD). MAFLD is thought to …

Remnant cholesterol predicts long-term mortality of patients with metabolic dysfunction–associated fatty liver disease

H Huang, Y Guo, Z Liu, Y Zeng… - The Journal of Clinical …, 2022 - academic.oup.com
Context Elevated serum remnant cholesterol independently predicts risks of cardiovascular
diseases. However, the association between remnant cholesterol and metabolic dysfunction …

The role of the immune system in the pathogenesis of NAFLD and potential therapeutic impacts of mesenchymal stem cell-derived extracellular vesicles

Z Moayedfard, F Sani, A Alizadeh… - Stem cell research & …, 2022 - Springer
Abstract Non-Alcoholic Fatty Liver Disease (NAFLD) is characterized by intra-hepatocyte
triglyceride accumulation and concomitant involvement of the immune system with …

[HTML][HTML] Novel metabolic classification for extrahepatic complication of metabolic associated fatty liver disease: a data-driven cluster analysis with international …

J Ye, X Zhuang, X Li, X Gong, Y Sun, W Wang, S Feng… - Metabolism, 2022 - Elsevier
Background Traditional classification systems of metabolic-associated fatty liver disease
(MAFLD) do not account for the high rate of extrahepatic complications. To create a new …