Artificial tears: a systematic review

DA Semp, D Beeson, AL Sheppard, D Dutta… - Clinical …, 2023 - Taylor & Francis
Artificial tears are the mainstay of dry eye disease management, but also have a role in
corneal abrasion and wound healing, pain and inflammation management, conjunctivitis …

[HTML][HTML] Hyaluronic acid: Its versatile use in ocular drug delivery with a specific focus on hyaluronic acid-based polyelectrolyte complexes

S Casey-Power, R Ryan, G Behl, P McLoughlin… - Pharmaceutics, 2022 - mdpi.com
Extensive research is currently being conducted into novel ocular drug delivery systems
(ODDS) that are capable of surpassing the limitations associated with conventional …

Trimethylated chitosan-coated flexible liposomes with resveratrol for topical drug delivery to reduce blue-light-induced retinal damage

H Gu, P Chen, X Liu, Y Lian, J Xi, J Li, J Song… - International Journal of …, 2023 - Elsevier
LED-related blue-light-induced damage can cause eye diseases. However, drug delivery in
patients with ocular diseases is faced with various challenges. In this study, we developed …

[HTML][HTML] Salidroside alleviates oxidative stress in dry eye disease by activating autophagy through AMPK-Sirt1 pathway

Q Liang, R Guo, JR Tsao, Y He, C Wang, J Jiang… - International …, 2023 - Elsevier
Dry eye disease (DED) is a multifactorial disease, and oxidative stress plays a crucial role in
its pathogenesis. Recently, multiple studies have shown that upregulation of autophagy can …

Hyaluronic acid-based nanoparticles to deliver drugs to the ocular posterior segment

H Jiang, Z Xu - Drug Delivery, 2023 - Taylor & Francis
Ocular posterior segment diseases such as uveitis, X-linked juvenile retinoschisis, or age-
related macular degeneration usually result in progressive and irreversible vision loss …

[HTML][HTML] Recent advances of ocular drug delivery systems: prominence of ocular implants for chronic eye diseases

M Mostafa, A Al Fatease, RG Alany, H Abdelkader - Pharmaceutics, 2023 - mdpi.com
Chronic ocular diseases can seriously impact the eyes and could potentially result in
blindness or serious vision loss. According to the most recent data from the WHO, there are …

[HTML][HTML] Hyaluronan: Sources, Structure, Features and Applications

K Valachová, ME Hassan, L Šoltés - Molecules, 2024 - mdpi.com
Hyaluronan (HA) is a non-sulfated glycosaminoglycan that is present in a variety of body
tissues and organs. Hyaluronan has a wide range of biological activities that are frequently …

[HTML][HTML] A critical appraisal of the physicochemical properties and biological effects of artificial tear ingredients and formulations

J Weng, MK Fink, A Sharma - International Journal of Molecular Sciences, 2023 - mdpi.com
Dry eye disease is among the most prevalent diseases affecting the ocular surface. Artificial
tears remain the cornerstone therapy for its management. There are currently a wide variety …

[HTML][HTML] Prospective bacterial and fungal sources of hyaluronic acid: A review

EV Shikina, RA Kovalevsky, AI Shirkovskaya… - Computational and …, 2022 - Elsevier
The unique biological and rheological properties make hyaluronic acid a sought-after
material for medicine and cosmetology. Due to very high purity requirements for hyaluronic …

Novel treatments for dry eye syndrome

E Roucaute, M Huertas-Bello, AL Sabater - Current Opinion in …, 2024 - Elsevier
Dry eye syndrome (DES) is a prevalent and multifactorial disease that leads to a self-
perpetuating cycle of inflammation and damage to the ocular surface. This results in …