A review of Dengvaxia®: development to deployment

SJ Thomas, IK Yoon - Human vaccines & immunotherapeutics, 2019 - Taylor & Francis
Dengue is the world's most prevalent and important arboviral disease. More than 50% of the
world's population lives at daily risk of infection and it is estimated more than 95 million …

[HTML][HTML] Viral membrane fusion

SC Harrison - Virology, 2015 - Elsevier
Membrane fusion is an essential step when enveloped viruses enter cells. Lipid bilayer
fusion requires catalysis to overcome a high kinetic barrier; viral fusion proteins are the …

The 3.8 Å resolution cryo-EM structure of Zika virus

D Sirohi, Z Chen, L Sun, T Klose, TC Pierson… - Science, 2016 - science.org
The recent rapid spread of Zika virus and its unexpected linkage to birth defects and an
autoimmune neurological syndrome have generated worldwide concern. Zika virus is a …

Biochemistry and molecular biology of flaviviruses

NJ Barrows, RK Campos, KC Liao, KR Prasanth… - Chemical …, 2018 - ACS Publications
Flaviviruses, such as dengue, Japanese encephalitis, tick-borne encephalitis, West Nile,
yellow fever, and Zika viruses, are critically important human pathogens that sicken a …

[HTML][HTML] Zika virus: History, epidemiology, transmission, and clinical presentation

BH Song, SI Yun, M Woolley, YM Lee - Journal of neuroimmunology, 2017 - Elsevier
Zika virus (ZIKV), a mosquito-borne positive-stranded RNA virus of the family Flaviviridae
(genus Flavivirus), is now causing an unprecedented large-scale outbreak in the Americas …

Evolutionary enhancement of Zika virus infectivity in Aedes aegypti mosquitoes

Y Liu, J Liu, S Du, C Shan, K Nie, R Zhang, XF Li… - Nature, 2017 - nature.com
Zika virus (ZIKV) remained obscure until the recent explosive outbreaks in French Polynesia
(2013–2014) and South America (2015–2016),,. Phylogenetic studies have shown that ZIKV …

Dengue virus and the host innate immune response

N Uno, TM Ross - Emerging microbes & infections, 2018 - Taylor & Francis
Dengue virus (DENV) is a mosquito-borne Flavivirus that is endemic in many tropical and
sub-tropical countries where the transmission vectors Aedes spp. mosquitoes resides. There …

The global ecology and epidemiology of West Nile virus

C Chancey, A Grinev, E Volkova… - BioMed research …, 2015 - Wiley Online Library
Since its initial isolation in Uganda in 1937 through the present, West Nile virus (WNV) has
become an important cause of human and animal disease worldwide. WNV, an enveloped …

Zika virus structure, maturation, and receptors

D Sirohi, RJ Kuhn - The Journal of infectious diseases, 2017 - academic.oup.com
The emergence of Zika virus (ZIKV) as a major public health threat has focused research on
understanding virus biology and developing a suite of strategies for disease intervention …

New insights into the immunopathology and control of dengue virus infection

G Screaton, J Mongkolsapaya, S Yacoub… - Nature Reviews …, 2015 - nature.com
Dengue virus poses a major threat to global public health: two-thirds of the world's
population is now at risk from infection by this mosquito-borne virus. Dengue virus causes a …