Leishmaniasis is a neglected tropical disease and remains a global concern for healthcare.
It is caused by an opportunistic protozoan parasite belonging to the genus Leishmania and …

The leishmaniases constitute a group of parasitic diseases caused by species of the
protozoan genus Leishmania. In humans it can present different clinical manifestations and …

AlphaFold2 and RoseTTAfold represent a transformative advance for predicting protein
structure. They are able to make very high-quality predictions given a high-quality alignment …

The leishmanin skin test was used for almost a century to detect exposure and immunity to
Leishmania, the causative agent of leishmaniasis, a major neglected tropical disease. Due …

Although viruses and bacteria have been known as agents of diseases since 1546, 250
years went by until the first vaccines against these pathogens were developed (1796 and …

Background Trypanosomatids of the genus Leishmania are parasites of mammals or reptiles
transmitted by bloodsucking dipterans. Many species of these flagellates cause important …

The genus Leishmania comprises a wide range of species, some of which are pathogenic to
humans and each of which has a different tissue preference, resulting in one of the three …

ABSTRACT CRISPR-Cas9 genome editing relies on an efficient double-strand DNA break
(DSB) and repair. Contrary to mammalian cells, the protozoan parasite Leishmania lacks the …

Genomes of strains of the zoophilic dermatophyte Microsporum canis from invasive
(disseminated and subcutaneous) and noninvasive (tinea capitis) infections were compared …

Background Leishmaniasis is a neglected tropical disease transmitted by infected sandflies
that results in diverse human pathologies contingent on the species of Leishmania …