Applications and advancements of nanoparticle-based drug delivery in alleviating lung cancer and chronic obstructive pulmonary disease

G De Rubis, KR Paudel, L Corrie, S Mehndiratta… - Naunyn-Schmiedeberg's …, 2024 - Springer
Lung cancer (LC) and chronic obstructive pulmonary disease (COPD) are among the
leading causes of mortality worldwide. Cigarette smoking is among the main aetiologic …

Berberine-loaded engineered nanoparticles attenuate TGF-β-induced remodelling in human bronchial epithelial cells

G De Rubis, KR Paudel, G Liu, V Agarwal… - Toxicology in Vitro, 2023 - Elsevier
Airway remodelling occurs in chronic respiratory diseases (CRDs) such as asthma and
chronic obstructive pulmonary disease (COPD). It is characterized by aberrant activation of …

Plant-based therapeutics for chronic obstructive pulmonary diseases: Nanoformulation strategies to overcome delivery challenges

S Kokkinis, M Singh, KR Paudel, G De Rubis, AB Saeid… - Food Bioscience, 2024 - Elsevier
Chronic obstructive pulmonary disease (COPD) is a widespread global health problem
marked by increasing airflow limitation and chronic airway inflammation. Conventional …

[HTML][HTML] Liposomal curcumin inhibits cigarette smoke induced senescence and inflammation in human bronchial epithelial cells

S Kokkinis, G De Rubis, KR Paudel, VK Patel… - … -Research and Practice, 2024 - Elsevier
Curcumin, the principal curcuminoid of turmeric (Curcuma longa extract), is very well known
for its multiple biological therapeutic activities, particularly its anti-inflammatory and …

Identification and pharmacological activities of secondary metabolites of Phytochemicals

OB Ovonramwen - 2022 - preprints.org
Plant secondary metabolites are organic compounds (alkaloids, flavonoids, phenolics,
tannins, anthraquinones, saponins, steroids, lignins, terpenes) produced by plant for self …

Phytochemical-based Nanodrug Delivery in Cancer Therapy

WH Almalki, NN Alotaibi, AAM Alayaf, AF Alotaibi… - International Journal of … - neliti.com
There are estimated to be 13.1 million cancer deaths by 2030, with 7.6 million deaths
occurring each year. Phytochemicals have long been used in traditional medicine to cure …