Antidepressants enter cells, organelles, and membranes
We begin by summarizing several examples of antidepressants whose therapeutic actions
begin when they encounter their targets in the cytoplasm or in the lumen of an organelle …
begin when they encounter their targets in the cytoplasm or in the lumen of an organelle …
Palmitoylation regulates human serotonin transporter activity, trafficking, and expression and is modulated by escitalopram
CR Brown, JD Foster - ACS Chemical Neuroscience, 2023 - ACS Publications
In the central nervous system, serotonergic signaling modulates sleep, mood, and cognitive
control. During serotonergic transmission, the synaptic concentration of serotonin is tightly …
control. During serotonergic transmission, the synaptic concentration of serotonin is tightly …
Discovery of periplasmic solute binding proteins with specificity for ketone bodies: β‐hydroxybutyrate binding proteins
BJ Kane, J Okuda‐Shimazaki, MM Andrews… - Protein …, 2024 - Wiley Online Library
Polyhydroxyalkanoates are a class of biodegradable, thermoplastic polymers which
represent a major carbon source for various bacteria. Proteins which mediate the …
represent a major carbon source for various bacteria. Proteins which mediate the …
[HTML][HTML] Epithelial and microbial determinants of colonic drug distribution
A dynamic epithelium and a rich microbiota, separated by multi-layered mucus, make up the
complex colonic cellular environment. Both cellular systems are characterized by high inter …
complex colonic cellular environment. Both cellular systems are characterized by high inter …
饮食干预治疗抑郁相关症状的研究进展
陈深册， 陈依明， 王凡， 张梦珂， 杨惟杰… - 上海交通大学学报 …, 2024 - xuebao.shsmu.edu.cn
抑郁症是一种常见的精神疾病, 目前全球有近16% 的人群受到抑郁相关症状的影响,
而在中国抑郁症患者的诊治率仅有9.5%. 抑郁症具有高发病率和低治愈率的特点 …
而在中国抑郁症患者的诊治率仅有9.5%. 抑郁症具有高发病率和低治愈率的特点 …
Interactive computational and experimental approaches improve the sensitivity of periplasmic binding protein-based nicotine biosensors for measurements in biofluids
We developed fluorescent protein sensors for nicotine with improved sensitivity. For
iNicSnFR12 at pH 7.4, the proportionality constant for∆ F/F0 vs [nicotine](δ-slope, 2.7 μM− 1) …
iNicSnFR12 at pH 7.4, the proportionality constant for∆ F/F0 vs [nicotine](δ-slope, 2.7 μM− 1) …
[图书][B] Genetically Encoded Biosensors for Ketamine and Other Rapidly Acting Antidepressants in Zebrafish and Cell Culture
Z Blumenfeld - 2023 - search.proquest.com
Over the past century, the development and use of treatments for depression has been one
of the most important projects in both neuroscience and medicine. Not only is relatively little …
of the most important projects in both neuroscience and medicine. Not only is relatively little …
Advances in dietary interventions for the treatment of depression-related symptoms
C Shentse, C Yiming, W Fan, Z Mengke… - Journal of Shanghai …, 2024 - xuebao.shsmu.edu.cn
Major depressive disorder (MDD) is a common mental illness. Currently, nearly 16% of the
global population is affected by depression-related symptoms, while the diagnosis and …
global population is affected by depression-related symptoms, while the diagnosis and …