Diverse processes in cancer are mediated by enzymes, which most proximally exert their
function through their activity. High-fidelity methods to profile enzyme activity are therefore …

Urinalysis is a widely used medical test for healthcare monitoring and disease diagnosis.
However, traditional urinalysis relies on endogenous biomarkers that have limited …

RNA interference (RNAi) therapeutics are an emerging class of medicines that selectively
target mRNA transcripts to silence protein production and combat disease. Despite the …

Although low-dose computed tomography screening improves lung cancer survival in at-risk
groups, inequality remains in lung cancer diagnosis due to limited access to and high costs …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and transmission
are generally known to be produced by respiratory droplets and aerosols from the oral cavity …

Analyzing the activity of proteases and their substrates is critical to defining the biological
functions of these enzymes and to designing new diagnostics and therapeutics that target …

Proteases play a crucial role, not only in physiological, but also in pathological processes,
such as cancer, inflammation, arthritis, Alzheimer's, and infections, to name but a few. Their …

Pharyngitis is an inflammatory condition of the pharynx and/or tonsils commonly seen in
both children and adults. Viruses and bacteria represent the most common encountered …

An accurate diagnosis is critical to reducing mortality in people with lower respiratory tract
infections (LRTIs). Current microbiological culture is time-consuming, and nucleic acid …

Conditional therapeutics that rely on disease microenvironment-specific triggers for
activation are a promising strategy to improve therapeutic cargos. Among the investigated …