Direct male development in chromosomally ZZ zebrafish

CA Wilson, P Batzel, JH Postlethwait - Frontiers in Cell and …, 2024 - frontiersin.org
The genetics of sex determination varies across taxa, sometimes even within a species.
Major domesticated strains of zebrafish (Danio rerio), including AB and TU, lack a strong …

[HTML][HTML] Significance of premature vertebral mineralization in zebrafish models in mechanistic and pharmaceutical research on hereditary multisystem diseases

J Van Wynsberghe, OM Vanakker - Biomolecules, 2023 - mdpi.com
Zebrafish are increasingly becoming an important model organism for studying the
pathophysiological mechanisms of human diseases and investigating how these …

Status of single cell RNA-seq for reproductive toxicology in zebrafish and the transcriptomic trade-off

ML Connell, DN Meyer, A Haimbaugh… - Current opinion in …, 2024 - Elsevier
The utilization of transcriptomic studies identifying profiles of gene expression, especially in
toxicogenomics (TGx), has catapulted next generation sequencing (NGS) to the forefront of …

Estrogen Signaling Inhibits the Expression of anti-Müllerian hormone (amh) and gonadal-soma-derived factor (gsdf) during the Critical Time of Sexual Fate …

Y Ruan, X Li, G Zhai, Q Lou, X Jin, J He… - International Journal of …, 2024 - mdpi.com
The mechanism of fish gonadal sex differentiation is complex and regulated by multiple
factors. It has been widely known that proper steroidogenesis in Leydig cells and sex-related …

The SARS-CoV-2 receptor and other key components of the Renin-Angiotensin-Aldosterone System related to COVID-19 are expressed in enterocytes in larval …

JH Postlethwait, MS Massaquoi… - Biology …, 2021 - journals.biologists.com
People with underlying conditions, including hypertension, obesity, and diabetes, are
especially susceptible to negative outcomes after infection with coronavirus SARS-CoV-2 …

Tandem Mass Tag-Based Quantitative Proteomics Analysis of Gonads reveals new insight into sexual reversal mechanism in Chinese soft-shelled turtles

T Zhou, G Chen, M Chen, Y Wang, G Zou, H Liang - Biology, 2022 - mdpi.com
Simple Summary The Chinese soft-shelled turtle has obvious sex dimorphism, which is an
important aquatic economic species in China. Exogenous hormones can cause the sexual …

PUBERTAL VIRILIZATION IN AN ADOLESCENT WITH 46, XY DISORDER OF SEXUAL DEVELOPMENT: A NOVEL MUTATION IN NR5A1 GENE

S Güneş, RD Sevim, ZM Yiğit, N Çulhacı… - Acta …, 2024 - pmc.ncbi.nlm.nih.gov
Background NR5A1 [Steroidogenic factor 1 (SF1)] is a nuclear receptor that is essential for
the development of gonads and adrenal glands as well as the establishment of …