[HTML][HTML] The human filaria Loa loa: Update on diagnostics and immune response

R Dieki, E Nsi-Emvo, JP Akue - Research and Reports in Tropical …, 2022 - ncbi.nlm.nih.gov
Loa loa loiasis was considered an anecdotal disease 30 years ago. Its spread in Equatorial
Africa and the side effects associated with mass drug administration programs against …

The African eye worm: current understanding of the epidemiology, clinical disease, and treatment of loiasis

M Ramharter, J Butler, G Mombo-Ngoma… - The Lancet Infectious …, 2024 - thelancet.com
Loa loa, the African eye worm, is a filarial pathogen transmitted by blood-sucking flies of the
genus Chrysops. Loiasis primarily affects rural populations residing in the forest and …

Distinct loiasis infection states and associated clinical and hematological manifestations in patients from Gabon

L Veletzky, KA Eberhardt, J Hergeth… - PLOS Neglected …, 2022 - journals.plos.org
Background Loiasis–a filarial disease endemic in Central and West Africa–is increasingly
recognized as significant individual and public health concern. While the understanding of …

Excess mortality associated with loiasis: confirmation by a new retrospective cohort study conducted in the Republic of Congo

MC Hemilembolo, AC Niama… - Open Forum …, 2023 - academic.oup.com
Abstract Background Loiasis (Loa loa filariasis) is considered a benign disease and is
currently not included in the World Health Organization's (WHO's) list of Neglected Tropical …

Implications for annual retesting after a test-and-not-treat strategy for onchocerciasis elimination in areas co-endemic with Loa loa infection: an observational cohort …

SDS Pion, H Nana-Djeunga… - The Lancet Infectious …, 2020 - thelancet.com
Background A test-and-not-treat (TaNT) strategy has been developed to prevent people with
high concentrations of circulating Loa loa microfilariae (> 20 000 microfilariae per mL) …

Association between arterial stiffness and Loa loa microfilaremia in a rural area of the Republic of Congo: A population-based cross-sectional study (the MorLo …

JT Campillo, V Dupasquier… - PLOS Neglected …, 2024 - journals.plos.org
Background Loa loa filariasis (loiasis) is still considered a relatively benign disease.
However, recent epidemiologic data suggest increased mortality and morbidity in L. loa …

Colorimetric and Real-Time Loop-Mediated Isothermal Amplification (LAMP) for Detection of Loa loa DNA in Human Blood Samples

B Febrer-Sendra, P Fernández-Soto, B Crego-Vicente… - Diagnostics, 2022 - mdpi.com
Loiasis, caused by the filarial nematode Loa loa, is endemic in Central and West Africa. Loa
loa has been associated with severe adverse reactions in high Loa-infected individuals …

Onchocerca volvulus microfilariae in the anterior chambers of the eye and ocular adverse events after a single dose of 8 mg moxidectin or 150 µg/kg ivermectin …

EM Kanza, A Nyathirombo, JP Larbelee, NO Opoku… - Parasites & …, 2024 - Springer
Background After ivermectin became available, diethylcarbamazine (DEC) use was
discontinued because of severe adverse reactions, including ocular reactions, in individuals …

Clinical and epidemiological features of imported loiasis in Beijing: a report from patients returned from Africa

X Li, M Huang, K Bi, Y Zou, F Wang, X Zheng… - BMC Infectious …, 2024 - Springer
Background Loiasis is one of the significant filarial diseases for people living in West and
Central Africa with wide endemic area but is not seen in China. As economy booms and …

Evaluation of a novel biplex rapid diagnostic test for antibody responses to Loa loa and Onchocerca volvulus infections

JT Campillo, MA Biamonte… - PLOS Neglected …, 2024 - journals.plos.org
Background Endemic to Central Africa, loiasis, caused by the vector-borne worm Loa loa,
affects approximately 10 million individuals. Clinical manifestations include transient …