Transforming growth factor β (TGF-β) has long been identified with its intensive involvement
in early embryonic development and organogenesis, immune supervision, tissue repair, and …

Idiopathic pulmonary fibrosis (IPF) is a fatal disease with incompletely understood aetiology
and limited treatment options. Traditionally, IPF was believed to be mainly caused by …

Idiopathic pulmonary fibrosis (IPF) is characterized by lung scarring and has no effective
treatment. Fibroblast-to-myofibroblast differentiation and myofibroblast proliferation and …

A major challenge in myocardial infarction (MI)-related heart failure treatment using
microRNA is the efficient and sustainable delivery of miRNAs into myocardium to achieve …

Myofibroblasts are the major cellular source of collagen, and their accumulation—via
differentiation from fibroblasts and resistance to apoptosis—is a hallmark of tissue fibrosis …

The lung is a complex organ with various cell types having distinct roles. Antisense
oligonucleotides (ASOs) have been studied in the lung, but it has been challenging to …

Idiopathic pulmonary fibrosis (IPF) is a rare disease of the lung with a largely unknown
etiology and a poor prognosis. Intriguingly, forms of familial pulmonary fibrosis (FPF) have …

Molecular patterns and pathways in idiopathic pulmonary fibrosis (IPF) have been
extensively investigated, but few studies have assimilated multiomic platforms to provide an …

Myofibroblasts escape apoptosis and proliferate abnormally under pathological conditions,
especially fibrosis; they synthesize and secrete a large amount of extracellular matrix (ECM) …

Pulmonary fibrosis (PF) is a type of interstitial pneumonia with complex etiology and high
mortality, characterized by progressive scarring of the alveolar interstitium and …