Introduction Candida albicans is the most prevalent fungal pathogen in humans. Due to the
development of drug resistance, there is today a need for new antifungal agents for the …

Regulated cell death (RCD) is a critical and active process that is controlled by specific
signal transduction pathways and can be regulated by genetic signals or drug interventions …

Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne disease
caused by a phlebovirus in the Bunyaviridae family. Infection can result in systemic …

Ethnopharmacological relevance The plants of the genus Peganum have a long history as a
Chinese traditional medicine for the treatment of cough, hypertension, diabetes, asthma …

Microtubule-affinity regulating kinase 4 (MARK4) is linked with the development of cancer,
diabetes and neurodegenerative diseases. Due to its direct role in the hyperphosphorylation …

The sphingosine kinase-1/sphingosine-1-phosphate pathway is linked with the cancer
progression and survival of the chemotherapy-challenged cells. Sphingosine kinase-1 …

Cancer, an uncontrolled and rapid proliferation of abnormal cells, has become one of the
leading cause of death worldwide. The development of resistance among the numerous …

Peganumine A (1), a new dimeric β-carboline alkaloid characterized by a unique 3, 9-
diazatetracyclo [6.5. 2.01, 9.03, 8] pentadec-2-one scaffold, was isolated from the seeds of …

Alkaloids are a wide family of basic N-containing natural products, whose research has
revealed bioactive compounds of pharmacological interest. Studies on these compounds …

Akkermansia muciniphila is a promising next-generation beneficial microbe due to its
natural presence in the mucus layer of the gut, its symbiotic ability to degrade mucus, and its …