Distant metastases in human papillomavirus‐related oropharyngeal squamous cell carcinoma: Systematic review and meta‐analysis

JR Crossley, LL Nelson, J Chou, JH Maxwell - Head & Neck, 2023 - Wiley Online Library
The prevalence of distant metastases (DM) in human papillomavirus (HPV)‐related
oropharyngeal squamous cell carcinoma (OPSCC) remains unknown. A PRISMA systematic …

The dual role of autophagy in HPV-positive head and neck squamous cell carcinoma: a systematic review

SA Kandathil, A Akhondi, L Kadletz-Wanke… - Journal of Cancer …, 2024 - Springer
Purpose Human papilloma virus (HPV)-positive head and neck squamous cell carcinoma
(HNSCC) displays distinct epidemiological, clinical, and molecular characteristics compared …

Radiomics predicts for distant metastasis in locally advanced human papillomavirus-positive oropharyngeal squamous cell carcinoma

B Rich, J Huang, Y Yang, W Jin, P Johnson, L Wang… - Cancers, 2021 - mdpi.com
Simple Summary There is strong evidence that locally advanced human papillomavirus
positive (HPV+) oropharyngeal squamous cell carcinoma (OPSCC) carries a significantly …

Inhibition of beta-catenin shows therapeutic potential in head and neck squamous cell carcinoma in vitro

T Maier, S Stoiber, E Gurnhofer, M Haas… - European Archives of …, 2023 - Springer
Beta-catenin is known to be a vital component of the canonical Wnt signaling cascade,
involved in the carcinogenesis of different solid tumors. We aimed to evaluate the effects of …

Targeting Wnt/Beta-catenin signaling in HPV-positive head and neck squamous cell carcinoma

FF Brkic, S Stoiber, T Maier, E Gurnhofer, L Kenner… - Pharmaceuticals, 2022 - mdpi.com
Wnt/Beta-Catenin signaling is involved in the carcinogenesis of different solid malignant
tumors. The interaction of Creb-binding protein (CBP) with Beta-Catenin is a pivotal …

In vitro antineoplastic effects of MK0752 in HPV-positive head and neck squamous cell carcinoma

S Varatanovic, S Stoiber, M Haas, A Lein… - Journal of Cancer …, 2023 - Springer
Purpose Gamma-secretase inhibitor MK0752 has shown a high therapeutic potential in
different solid malignant tumors. Up to now, its antineoplastic effects were not investigated in …

In vitro effects of gamma-secretase inhibition in HPV-positive and HPV-negative head and neck squamous cell carcinoma

S Varatanovic, T Maier, S Al-Gboore, S Stoiber… - Investigational New …, 2023 - Springer
Background New chemotherapy agents are warranted for head and neck squamous cell
carcinoma (HNSCC), particularly for incidence-rising HPV-positive tumors. Based on the …

Concurrent high risk HPV35, HPV45, and HPV59 infections in prostate and bladder cancer tissues of a single patient: A case report

MY Ahmed, MO Cakir, NA Salman, S Sandhu… - Heliyon, 2024 - cell.com
Human papillomavirus (HPV) infections, primarily transmitted through sexual contact, have
been linked to various cancers, including cervical, penile, anal, oropharynx, breast, and …

Surgical salvage of human papillomavirus–positive oropharyngeal cancer: Secondary analysis of a randomized controlled trial

DL Quan, JS Grauer, PR Sunkara, JD Cramer - Cancer, 2023 - Wiley Online Library
Background Survival outcomes are generally better for human papillomavirus–associated
oropharyngeal squamous cell carcinoma (HPV+ OPSCC) than other forms of head and neck …

Trans Oral Robotic Surgery for HPV‐Negative Oropharyngeal Squamous Cell Carcinoma: Follow‐Up on Oncological and Functional Outcomes

K Azalmad, K Lambercy, A Beharry, N Piazzon… - Head & …, 2024 - Wiley Online Library
Background The efficacy of transoral robotic surgery (TORS) for HPV‐negative
oropharyngeal cancers (OPSCC) is less explored, especially regarding long‐term outcomes …