Serotonin, also known as 5-hydroxytryptamine (5-HT), is a metabolite of tryptophan and is
reported to modulate the development and neurogenesis of the enteric nervous system, gut …

Abstract Serotonin (5-HT) has been recognized for decades as an important signalling
molecule in the gut, but it is still revealing its secrets. Novel gastrointestinal functions of 5-HT …

The intestinal epithelium must balance efficient absorption of nutrients with partitioning
commensals and pathogens from the bodies' largest immune system. If this crucial barrier …

The gastrointestinal tract is innervated by several distinct populations of neurons, whose cell
bodies either reside within (intrinsic) or outside (extrinsic) the gastrointestinal wall. Normally …

Abstract Serotonin (5-hydroxytryptamine; 5-HT) is best known as a neurotransmitter critical
for central nervous system (CNS) development and function. 95% of the body's serotonin …

Inflammatory bowel disease is a chronic intestinal inflammatory condition, the pathology of
which is incompletely understood. Gut inflammation causes significant changes in neurally …

Summary Background Serotonin (5‐hydroxytryptamine, 5‐HT) is an important mediator of
every major gut‐related function. Recent investigations also suggest that 5‐HT can influence …

Phytosterols, besides hypocholesterolemic effect, present anti-inflammatory properties. Little
information is available about their efficacy in Inflammatory Bowel Disease (IBD). Therefore …

Various studies have described abnormalities of the enteric nervous system (ENS) in tissue
samples from patients with chronic idiopathic inflammatory bowel diseases (IBD). The …

Lactobacillus plantarum AR495 is a widely used probiotic for the treatment of various
digestive diseases, including irritable bowel syndrome (IBS). However, the specific …