The sarcoplasmic reticulum (SR) of smooth muscles presents many intriguing facets and
questions concerning its roles, especially as these change with development, disease, and …

Low-level laser (LLL) irradiation has been reported to promote neuronal differentiation, but
the mechanism remains unclear. Brain-derived neurotrophic factor (BDNF) has been …

Low extracellular pH (pHe) occurs in a number of clinical conditions and sensitizes to the
development of pancreatitis. The mechanisms responsible for this sensitization are …

Changes in K+ conductances and their contribution to membrane depolarization in the
setting of an acidic pH environment have been studied in myocytes from aortic smooth …

Metabolic acidosis is associated with various clinical situations including diabetes mellitus
and renal diseases. The aim of this study was to investigate the effects of acidosis on the …

Calcium overload during hypoxia and reoxygenation exerts deleterious effects in endothelial
and smooth muscle cells but potential effects of sodium-proton exchanger (NHE) inhibitors …

The effects of acidosis were investigated on the resting and precontracted aortas from Wistar
and Wistar Kyoto (WKY) rats. Decrease in pH from 7.4 to 6.5, having no effect on the resting …

Aim: This study was conducted to investigate the mechanism of acidic pH‐induced
contraction (APIC) with regard to Ca2+ handling using isometric tension recording …

This study was performed to test the hypothesis that activation of protein kinase C (PKC) is a
mechanism underlying the acidic pH-induced contraction (APIC) in spontaneously …

Hydrogen ion concentration (H+) is an important regulator of many cellular functions
including contractility of the vascular smooth muscle cells. In many physiological and …