Stability Oracle: a structure-based graph-transformer framework for identifying stabilizing mutations
Engineering stabilized proteins is a fundamental challenge in the development of industrial
and pharmaceutical biotechnologies. We present Stability Oracle: a structure-based graph …
and pharmaceutical biotechnologies. We present Stability Oracle: a structure-based graph …
Asymmetric Synthesis of α-Chloroamides via Photoenzymatic Hydroalkylation of Olefins
Photoenzymatic intermolecular hydroalkylations of olefins are highly enantioselective for
chiral centers formed during radical termination but poorly selective for centers set in the C …
chiral centers formed during radical termination but poorly selective for centers set in the C …
Two sequence-and two structure-based ML models have learned different aspects of protein biochemistry
Deep learning models are seeing increased use as methods to predict mutational effects or
allowed mutations in proteins. The models commonly used for these purposes include large …
allowed mutations in proteins. The models commonly used for these purposes include large …
Exploring protein biochemistry with deep learning
AV Kulikova - 2023 - repositories.lib.utexas.edu
Deep learning has become widely used in biological sciences. More specifically, the
development of protein deep learning models has leveraged the evergrowing collection of …
development of protein deep learning models has leveraged the evergrowing collection of …