NADPH-generating systems in bacteria and archaea

SK Spaans, RA Weusthuis, J Van Der Oost… - Frontiers in …, 2015 - frontiersin.org
Reduced nicotinamide adenine dinucleotide phosphate (NADPH) is an essential electron
donor in all organisms. It provides the reducing power that drives numerous anabolic …

The acetate switch

AJ Wolfe - Microbiology and molecular biology reviews, 2005 - Am Soc Microbiol
To succeed, many cells must alternate between life-styles that permit rapid growth in the
presence of abundant nutrients and ones that enhance survival in the absence of those …

Stochasticity of metabolism and growth at the single-cell level

DJ Kiviet, P Nghe, N Walker, S Boulineau… - Nature, 2014 - nature.com
Elucidating the role of molecular stochasticity in cellular growth is central to understanding
phenotypic heterogeneity and the stability of cellular proliferation. The inherent stochasticity …

[图书][B] Analysis of biological networks

BH Junker, F Schreiber - 2008 - Wiley Online Library
Analysis of biological networks ANALYSIS OF BIOLOGICAL NETWORKS Page 2
ANALYSIS OF BIOLOGICAL NETWORKS EDITED BY BJO RN H. JUNKER and FALK …

The global, ppGpp‐mediated stringent response to amino acid starvation in Escherichia coli

MF Traxler, SM Summers, HT Nguyen… - Molecular …, 2008 - Wiley Online Library
The stringent response to amino acid starvation, whereby stable RNA synthesis is curtailed
in favour of transcription of amino acid biosynthetic genes, is controlled by the alarmone …

Acetate as a potential feedstock for the production of value-added chemicals: metabolism and applications

Y Kim, S Lama, D Agrawal, V Kumar, S Park - Biotechnology Advances, 2021 - Elsevier
Acetate is regarded as a promising carbon feedstock in biological production owing to its
possible derivation from C 1 gases such as CO, CO 2 and methane. To best use of acetate …

The PEP—pyruvate—oxaloacetate node as the switch point for carbon flux distribution in bacteria: We dedicate this paper to Rudolf K. Thauer, Director of the Max …

U Sauer, BJ Eikmanns - FEMS microbiology reviews, 2005 - academic.oup.com
In many organisms, metabolite interconversion at the phosphoenolpyruvate (PEP)–pyruvate–
oxaloacetate node involves a structurally entangled set of reactions that interconnects the …

Metabolic network structure determines key aspects of functionality and regulation

J Stelling, S Klamt, K Bettenbrock, S Schuster… - Nature, 2002 - nature.com
The relationship between structure, function and regulation in complex cellular networks is a
still largely open question,,. Systems biology aims to explain this relationship by combining …

Growing E. coli to high cell density—a historical perspective on method development

J Shiloach, R Fass - Biotechnology advances, 2005 - Elsevier
E. coli is the major bacterial platform for expressing simple heterologous proteins. Growing
E. coli to high densities has been the subject of numerous studies since the early 1970s …

Identification of the CRP regulon using in vitro and in vivo transcriptional profiling

D Zheng, C Constantinidou, JL Hobman… - Nucleic acids …, 2004 - academic.oup.com
The Escherichia coli cyclic AMP receptor protein (CRP) is a global regulator that controls
transcription initiation from more than 100 promoters by binding to a specific DNA sequence …