Recent research has provided new insights on the epidemiology, pathology and
immunology of canine leishmaniosis (CanL) and its genetic basis. The prevalence of …

The control of infection by Leishmania infantum (syn. Leishmania chagasi) in dogs is
essential to stop the current spread of zoonotic visceral leishmaniasis. The past few years …

Visceral Leishmaniasis is a chronic zoonosis and, if left untreated, can be fatal. Infected
dogs have decreased cellular immunity (Th1) and develop a potent humoral response (Th2) …

Progressive splenomegaly is a hallmark of visceral leishmaniasis in humans, canids, and
rodents. In experimental murine visceral leishmaniasis, splenomegaly is accompanied by …

Canine visceral leishmaniasis (CVL) is a severe and fatal systemic chronic inflammatory
disease. We investigated the alterations in, and potential associations among, antioxidant …

Visceral leishmaniasis (VL) causes extensive splenic pathology that contributes to
dysfunctional immune responses, in part through displacement and destruction of cell …

Receptor tyrosine kinases are involved in multiple cellular processes, and drugs that inhibit
their action are used in the clinic to treat several types of cancer. However, the value of …

We propose that canine visceral leishmaniasis (CVL) is a systemic fibrotic disease, as
evidenced by the wide distribution of fibrosis that we have found in the dogs suffering from …

Background Nodular lymphoid hyperplasia (NLH) is one of the most common non-
neoplastic splenic lesions in dogs, especially in old ones, showing a splenic enlargement …

The objectives of this work were to study some pathological aspects of kidneys obtained
from dogs naturally infected with Leishmania infantum and from dogs experimentally …