Exosomes (Exo) are small vesicles produced by melanoma cells and the accessory cells of
the tumor microenvironment. They emerge via both classical and direct pathways and …

The tumor microenvironment (TME) plays a crucial role in cancer progression and immune
evasion, partially mediated by the activity of the TME-derived exosomes. These extracellular …

Hypoxia is a common feature of solid tumors. It is closely related to tumor progression.
Exosomal microRNAs derived from cancers are considered to be mediators between cancer …

MicroRNAs (miRNA), small noncoding RNAs that regulate gene expression, exist not only in
cells but also in a variety of body fluids. These circulating miRNAs could enable intercellular …

Both exosomes and soluble factors have been implicated in the generation of an
immunosuppressive tumour microenvironment. Determining the contribution of each …

Background The period of time when the embryo and the endometrium undergo significant
morphological alterations to facilitate a successful implantation—known as “window of …

Since tyrosine phosphorylation is reversible and dynamic in vivo, the phosphorylation state
of proteins is controlled by the opposing roles of protein tyrosine kinases (PTKs) and protein …

Exosomes produced by tumor cells have been shown to reprogram functions of human
immune cells. Molecular cargos of exosomes isolated from supernatants of HPV (+) and …

Cancer progression is a polygenic procedure in which the exosomes can function as
substantial roles. Exosomes are tiny, phospholipid bilayer membrane nanovesicles of …

Cutaneous melanoma is an aggressive cancer type derived from melanocytes and its
incidence has rapidly increased worldwide. Despite the vast improvement in therapy …